# Assessment of Comorbidities in Chronic Obstructive Pulmonary Disease Patients by Chest High Resolution Computed Tomography (HRCT)

**Authors:** Ecaterina Iavrumov, Dumitru Cravcenco, Alexandr Ceasovschih, Pradeesh Sivapalan, Nikos Siafakas, Alexandru Corlateanu

PMC · DOI: 10.3390/jcm15020785 · 2026-01-19

## TL;DR

This study shows that chest HRCT scans are effective in identifying multiple comorbidities in COPD patients, which can improve their clinical management.

## Contribution

The study demonstrates the utility of HRCT in detecting a wide range of comorbidities in COPD patients beyond standard assessments.

## Key findings

- Chest HRCT identified comorbidities in 96% of COPD patients, with 68% having three or more.
- Common comorbidities included coronary artery calcification (66%) and osteoporosis (83%).
- Most patients (69%) were classified as GOLD type E, indicating severe COPD.

## Abstract

Purpose: Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory condition often accompanied by various comorbidities that significantly affect patient outcomes. High resolution computed tomography (HRCT) has emerged as a valuable tool for diagnosing and managing COPD-related comorbidities. This study aimed to explore the impact of chest computed tomography (CT) imaging in identifying and characterizing comorbidities in COPD patients. Methods: The study was conducted on 99 patients with COPD, the median age of the study population was 70.0 years (Q1–Q3: 62.0–75.0); 86% were men (85), and 14% were women (14). All patients underwent chest HRCT to identify the presence of comorbidities. Results: According to the GOLD classification (ABE groups), 3% were type A, 27% were type B, and 69% were type E. The prevalence of comorbidities identified on chest HRCT was reported as 66% for coronary artery calcification (CAC), 83% for osteoporosis, 36% for pulmonary artery enlargement (PAE), 31% for emphysema, 19% for bronchiectasis, 17% for hiatal hernia, 14% for lung cancer, 12% pulmonary infections, and 3% for interstitial abnormalities. In 4%, there were no comorbidities, one comorbidity was found in 11%, two comorbidities in 17%, and three comorbidities and more in 68% of cases. Conclusions: Chest HRCT imaging serves as a valuable tool for identifying and assessing comorbidities in patients with COPD. Incorporating chest CT imaging into the routine evaluation of COPD patients may contribute to a more comprehensive understanding of their condition and lead to better clinical outcomes.

## Linked entities

- **Diseases:** Chronic Obstructive Pulmonary Disease (MONDO:0005002), osteoporosis (MONDO:0005298), emphysema (MONDO:0004849), bronchiectasis (MONDO:0004822), hiatal hernia (MONDO:0007721), lung cancer (MONDO:0005138)

## Full-text entities

- **Diseases:** emphysema (MESH:D004646), pulmonary infections (MESH:D012141), COPD (MESH:D029424), CAC (MESH:D003324), bronchiectasis (MESH:D001987), interstitial abnormalities (MESH:D065167), PAE (MESH:D000071079), lung cancer (MESH:D008175), osteoporosis (MESH:D010024), hiatal hernia (MESH:D006551)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12842085/full.md

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Source: https://tomesphere.com/paper/PMC12842085