# Intralesional Corticosteroid Injections in the Treatment of Oral Lichen Planus—A Narrative Review

## TL;DR

This review examines how corticosteroid injections help treat oral lichen planus, a chronic mouth condition, by reducing pain and healing lesions safely.

## Contribution

The review evaluates the effectiveness and safety of intralesional corticosteroid injections for treating oral lichen planus.

## Key findings

- Triamcinolone acetonide injections at 10–40 mg/mL reduced pain and healed OLP lesions.
- Injections showed minor adverse effects and were considered safe and effective.
- The treatment is recommended for patients with symptomatic OLP.

## Abstract

Background: Oral lichen planus (OLP) is a chronic inflammatory autoimmune disease. Certain clinical forms of the disease may cause significant discomfort and negatively impact patients’ quality of life. The first-line treatment is topical corticosteroids. The purpose of this narrative review is to evaluate the influence of corticosteroid injections in the treatment of OLP. Methods: A search of the literature was conducted in October 2025 using the following databases: PubMed, Web of Science, Scopus, and Cochrane. Results: Fifteen studies were evaluated. Injections with triamcinolone acetonide at a concentration of 10–40 mg/mL at weekly intervals demonstrated efficacy in reducing pain and healing OLP lesions in these studies. They showed minor adverse effects. Conclusions: Noting the limitations of this narrative review, intralesional corticosteroid injections are an effective and safe method of treating OLP. They should be considered in patients with symptomatic OLP.