# The Impact of Compassion Fatigue on the Psychological Well-Being of Nurses Caring for Patients with Dementia: A Cross-Sectional Post-COVID-19 Data Analysis

**Authors:** Maria Topi, Paraskevi Tsioufi, Evangelos C. Fradelos, Foteini Malli, Evmorfia Koukia, Polyxeni Mangoulia

PMC · DOI: 10.3390/healthcare14020224 · 2026-01-16

## TL;DR

This study explores how compassion fatigue affects the mental health of nurses caring for dementia patients in Greece, especially during the pandemic.

## Contribution

The paper identifies specific factors like gender and income that influence compassion satisfaction among dementia care nurses.

## Key findings

- Female gender and higher family income were positively linked to compassion satisfaction.
- Anxiety and depression symptoms correlated with lower compassion satisfaction and higher burnout.
- Over 40% of nurses rated their work environment as favorable, while nearly half showed low burnout levels.

## Abstract

Background/Objectives: Nurses are susceptible to compassion fatigue due to the nature of their professional responsibilities. Factors contributing to this vulnerability include daily patient interactions and organizational elements within their work environment, as well as work-related stress and sociodemographic characteristics, including age, marital status, years of professional experience, and, notably, gender. This research investigates the relationship between compassion fatigue and the levels of anxiety and depression, as well as the professional quality of life among nurses providing care to dementia patients in Greece. Methods: A cross-sectional survey was carried out with 115 nurses working in dementia care centers in Greece. The Hospital Anxiety and Depression Scale (HADS), the Professional Quality of Life Scale (ProQOL-5), and the participants’ personal, demographic, and professional information were all included in an electronic questionnaire. Multiple regression analysis was used. Results: A total of 42.6% of nurses rated their working environment as favorable. Additionally, 23.5% of the sample exhibited high levels of compassion satisfaction, whereas 46.1% demonstrated low levels of burnout. Female gender (p = 0.022) and a higher family income (p = 0.046) was positively associated with compassion satisfaction. Regression analysis indicated that elevated symptoms of anxiety and depression were found to correlate with decreased compassion satisfaction, increased burnout, and heightened secondary post-traumatic stress. Conclusions: Engaging in the care of patients with dementia, particularly throughout the pandemic period, has underscored a pronounced susceptibility to compassion fatigue, physical fatigue, pain, psychological stress, and a reduced quality of life. These results highlight the importance for nursing management to adopt specific organizational measures, including proper staffing levels, balancing workloads, and conducting routine mental health assessments.

## Linked entities

- **Diseases:** dementia (MONDO:0001627)

## Full-text entities

- **Diseases:** depression (MESH:D003866), Compassion Fatigue (MESH:D000068376), Hospital Anxiety and Depression (MESH:D001007), Post-COVID-19 (MESH:D000094024), pain (MESH:D010146), burnout (MESH:D002055), post-traumatic stress (MESH:D013313), fatigue (MESH:D005221), Dementia (MESH:D003704)
- **Species:** Homo sapiens (human, species) [taxon 9606]

---
Source: https://tomesphere.com/paper/PMC12841586