# Bronchiolo-arterial fistula management in a patient with Loeys-Dietz syndrome using a multidisciplinary approach

**Authors:** Meredith Otley, Muhanned Kheder, Jeremy Wood, Chris Lightfoot, Michael Rivers-Bowerman, Mathieu Castonguay, Daniel French

PMC · DOI: 10.1093/jscr/rjag006 · 2026-01-27

## TL;DR

A patient with Loeys-Dietz syndrome had chronic hemoptysis successfully treated with surgery after other methods failed.

## Contribution

Demonstrates successful multidisciplinary management of a rare bronchiolo-arterial fistula in a complex patient case.

## Key findings

- Left upper lobectomy resolved persistent hemoptysis in a patient with Loeys-Dietz syndrome.
- Pathology confirmed the presence of a bronchiolo-arterial fistula.
- No recurrence of hemoptysis was observed after 2 years of follow-up.

## Abstract

Bronchiolo-arterial fistulae are rare occurrences that can lead to hemoptysis. In general, persistent hemoptysis has a broad range of causes and management options. Surgery is often used in cases where conservative approaches have failed. In this case study, we present a 43-year-old woman with Loeys-Dietz syndrome, a connective tissue disorder, who developed chronic persistent hemoptysis after multiple aortic operations. The hemoptysis did not resolve with antibiotics, corticosteroids, and coil embolization. Based on multidisciplinary consensus, a left upper lobectomy was performed, with no recurrence of hemoptysis after 2 years of follow-up. Pathology revealed a bronchiolo-arterial fistula.

## Linked entities

- **Diseases:** Loeys-Dietz syndrome (MONDO:0018954)

## Full-text entities

- **Diseases:** Bronchiolo (MESH:D002282), hemoptysis (MESH:D006469), connective tissue disorder (MESH:D003240), fistula (MESH:D005402), Loeys-Dietz syndrome (MESH:D055947)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12840577/full.md

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Source: https://tomesphere.com/paper/PMC12840577