# Long-Term Clinical Outcome of a Surgically Treated Ameloblastoma: Over a Decade of Follow-Up and Oral Rehabilitation

**Authors:** Ruxandra Elena Luca, Ciprian Ioan Roi, Alexandra Roi, Eduard Gîdea-Paraschivescu

PMC · DOI: 10.3390/dj14010039 · 2026-01-07

## TL;DR

A 16-year-old patient with an ameloblastoma underwent successful surgical removal and oral rehabilitation, with no recurrence after 11 years.

## Contribution

This case demonstrates successful long-term management of an extensive ameloblastoma through interdisciplinary surgical and prosthetic approaches.

## Key findings

- No tumour recurrence was observed after an 11-year follow-up.
- Implant-supported prosthetic rehabilitation restored masticatory function and aesthetics successfully.
- The case supports interdisciplinary approaches for managing extensive ameloblastomas.

## Abstract

Background: Ameloblastomas account for roughly 1% of all jaw tumours and cysts, typically manifesting as slow-growing, painless swellings that expand both buccal and lingual cortical plates and may infiltrate adjacent soft tissue, often leading to a delayed diagnosis. These benign tumours, characterized by local invasiveness, originate from epithelial tissues and may develop from dental lamina cell rests, the enamel apparatus, the epithelial lining of odontogenic cysts, or basal epithelial cells of the oral mucosa. Methods: This paper aims to describe the comprehensive and interdisciplinary management of an extensive ameloblastoma in a 16-year-old patient, emphasizing the diagnostic challenges, surgical resection, reconstructive procedures, and subsequent oral rehabilitation. Results: At the eleven-year follow-up, clinical and radiographic examinations showed no signs of tumour recurrence. The patient presented no symptoms, indicating neither pain nor functional impairment. The prosthetic rehabilitation utilizing implant-supported fixed restorations was successfully completed, resulting in satisfactory masticatory function and aesthetics. This case adds to the existing evidence on the management of extensive ameloblastomas by demonstrating successful long-term outcomes following interdisciplinary surgical reconstruction and rehabilitation. Conclusions: The presented case highlights the complexity of restoring the lost tissues and functions, as well as the long-term clinical, functional, and aesthetic outcomes over an eleven-years follow-up period.

## Linked entities

- **Diseases:** ameloblastoma (MONDO:0017795)

## Full-text entities

- **Diseases:** benign tumours (MESH:D009369), cysts (MESH:D003560), Ameloblastoma (MESH:D000564), odontogenic cysts (MESH:D009807), jaw tumours (MESH:D007573), pain (MESH:D010146), swellings (MESH:D004487)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

14 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12840559/full.md

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Source: https://tomesphere.com/paper/PMC12840559