# Optimal Timing of Inguinal Hernia Repair in Premature Infants: A Retrospective Study

**Authors:** Joshua Z. E. Yau, Paul C. Y. Chang, Nien-Lu Wang, Jin-Cherng Sheu, Hsuan Huang, Yi-Ting Yeh

PMC · DOI: 10.3390/children13010160 · 2026-01-22

## TL;DR

Repairing inguinal hernias in premature infants before 38 weeks postmenstrual age increases respiratory risks, especially in low-weight or oxygen-dependent infants.

## Contribution

Identifies optimal timing for hernia repair in premature infants to reduce postoperative respiratory complications.

## Key findings

- Early hernia repair before 38 weeks PMA is linked to higher postoperative respiratory complications.
- Infants with preoperative oxygen dependence and weight <2.8 kg face greater risks.
- Repair after 38 weeks PMA is associated with fewer respiratory complications.

## Abstract

What are the main findings?
Early inguinal hernia repair in premature infants with a PMA of <38 weeks is associated with a higher risk of postoperative respiratory complicationsPreoperative oxygen dependence and body weight < 2.8 kg at the time of surgery are the main contributing risk factors

Early inguinal hernia repair in premature infants with a PMA of <38 weeks is associated with a higher risk of postoperative respiratory complications

Preoperative oxygen dependence and body weight < 2.8 kg at the time of surgery are the main contributing risk factors

What are the implications of the main findings?
While advances in anesthesia and surgical techniques facilitate earlier intervention, the decision to proceed with repair before hospital discharge (usually around 2.5 to 2.8 kg) requires cautious risk stratificationIf early repair is chosen, postoperative protocols must be adjusted to include a prolonged observation period to ensure the timely management of potential respiratory complications

While advances in anesthesia and surgical techniques facilitate earlier intervention, the decision to proceed with repair before hospital discharge (usually around 2.5 to 2.8 kg) requires cautious risk stratification

If early repair is chosen, postoperative protocols must be adjusted to include a prolonged observation period to ensure the timely management of potential respiratory complications

Background/Objectives: The optimal timing for inguinal hernia repair in premature infants remains controversial. Most premature patients in our institution undergo repair just before discharge. This study evaluates postoperative complications in premature patients and proposes the optimal timing for hernia repair. Methods: A retrospective single-center review was conducted between January 2020 and November 2023. All infants undergoing hernia repair as inpatients under 50 weeks postmenstrual age (PMA) were included. Data collected included demographic details, perioperative characteristics, and postoperative outcomes. Results: A total of 202 patients were analyzed. Forty-five patients underwent surgery before 38 weeks PMA (early group), and 157 after 38 weeks PMA (late group). The early group had significantly lower gestational age, lower body weight, and more comorbidities. Postoperative respiratory complications were more frequent in the early group. Conclusions: Repair after 38 weeks PMA is associated with fewer respiratory complications while earlier repair increases transient airway support requirements.

## Linked entities

- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** respiratory complications (MESH:D012140), Inguinal Hernia (MESH:D006552), hernia (MESH:D006547)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12840359