# Digital Technologies in Diagnosing Solitary Median Maxillary Central Incisor Syndrome

## TL;DR

This paper reports a case of Solitary Median Maxillary Central Incisor Syndrome and highlights the importance of early diagnosis for orthodontists.

## Contribution

The study contributes a new clinical case report of SMMCI syndrome in orthodontic practice.

## Key findings

- A case of SMMCI syndrome was identified and reported in a patient from Poznan University Medical Sciences.
- Early diagnosis is crucial for identifying potential developmental abnormalities associated with SMMCI.

## Abstract

Solitary Median Maxillary Central Incisor Syndrome is unique congenital developmental defect affecting midline structures of the head and the body. The prevalent symptom is a solitary median incisor of the maxilla in primary and secondary dentition, which is positioned exactly in the midline of the alveolus. Other abnormalities that are characteristic of the syndrome include holoprosencephaly, nasal cavity anomalies, cleft palate–lip, hypotelorism, and microcephaly. It is estimated to occur in 1:50,000 live births, with female gender predilection. The cause of the syndrome is related to midline defects in the migration and connection of the prechordal mesoderm between the 35th and 38th days post-conception. Early diagnosis of SMMCI is important for practicing orthodontists, as it may be a symptom of other developmental abnormalities. The aim of this study is to report a case of SMMCI syndrome in a patient treated in the Department of Orthodontics and Facial Malformation of the University of Medical Sciences in Poznan.