# Breast Cancer and Cardiovascular Risk: The Role of Dyslipidemia, Inflammation and Obesity

## TL;DR

This paper reviews the link between breast cancer and cardiovascular risk factors like obesity and inflammation in Serbia.

## Contribution

It emphasizes the need for more clinical studies to clarify the mechanisms connecting these conditions.

## Key findings

- There is a known connection between cardiovascular risk and breast cancer.
- Metabolic syndrome, inflammation, and obesity are linked to breast cancer.
- More multicenter studies are needed to confirm these associations.

## Abstract

Cardiovascular diseases, malignancy, and diabetes mellitus are the most common chronic non-communicable diseases affecting the population in Serbia. According to The Cancer Registry of the Republic of Serbia, breast cancer is the most common cancer affecting women in Serbia. Every year, 4600 women get diagnosed with BC, and 1600 women die from this disease. Every eighth woman in Serbia is diagnosed with BC. This review aims to summarize clinical and theoretical information about breast cancer, metabolic syndrome and cardiovascular risk connection. The literature search was conducted through PubMed, Google Scholar and cross-references in January 2024. We concluded that although there is a well-established connection between cardiovascular risk, metabolic syndrome, inflammation, dyslipidemia, obesity, diabetes mellitus and breast cancer, more multicenter prospective clinical studies are needed to establish the precise association and pathophysiological mechanisms.