# Cancer Screening and Prevention in MENA and Mediterranean Populations: A Multi-Level Analysis of Barriers, Knowledge Gaps, and Interventions Across Indigenous and Diaspora Communities

**Authors:** Sebahat Gozum, Omar F. Nimri, Mohammed Abdulridha Merzah, Rui Vitorino

PMC · DOI: 10.3390/diseases14010010 · Diseases · 2025-12-28

## TL;DR

This paper reviews cancer screening challenges in MENA and Mediterranean regions, highlighting inequalities and proposing solutions to improve access for vulnerable women.

## Contribution

The paper provides a multi-level analysis of cancer screening barriers and interventions across indigenous and diaspora communities in MENA and Mediterranean regions.

## Key findings

- Inequalities in cancer screening access are driven by fragmented policies, socio-cultural resistance, and infrastructure gaps.
- Community-led outreach and mobile screening programs show promise in improving access to cancer prevention.
- Systemic and cultural barriers persist even in well-equipped facilities, affecting both indigenous and diaspora populations.

## Abstract

Cancer is one of the biggest health burdens for women in the Middle East and North Africa (MENA), with the incidence of breast, cervical and colorectal cancer on the rise. Although preventive measures such as the HPV vaccination and population-based screening are available, access to them remains very unequal. Women in rural, low-income and refugee communities face additional barriers, cultural stigmatisation, low health literacy, gender norms and fragile health systems, leading to delayed diagnoses and poorer outcomes. This review summarises the results of 724 peer-reviewed publications to assess the current situation of cancer screening in MENA and Mediterranean countries. The studies were classified into four dimensions: cancer type (breast, cervical, colorectal), behavioural constructs (awareness, uptake, education), vulnerability factors (e.g., migrants, refugees, low-literacy groups), and geography (indigenous MENA populations versus diaspora and Mediterranean immigrant communities). The results show large inequalities in access and participation due to fragmented policies, socio-cultural resistance and infrastructure gaps. Nevertheless, promising approaches are emerging: community-led outreach, mobile screening programmes, AI-assisted triage and culturally appropriate digital health interventions. Comparisons between the local and diaspora populations make it clear that systemic and cultural barriers persist even in well-equipped facilities. Closing the screening gap requires a culturally sensitive, digitally enabled and policy aligned approach. Key priorities include engaging religious and community leaders, promoting men’s engagement in women’s health and securing sustainable funding. With coordinated action across all sectors, MENA countries can build inclusive screening programmes that reach vulnerable women and reduce preventable cancer mortality.

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989), cervical cancer (MONDO:0002974), colorectal cancer (MONDO:0005575)

## Full-text entities

- **Diseases:** breast, cervical and colorectal cancer (MESH:D001943), breast (MESH:D061325), colorectal (MESH:D015179), Cancer (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

54 references — full list in the complete paper: https://tomesphere.com/paper/PMC12839870/full.md

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Source: https://tomesphere.com/paper/PMC12839870