# Active Rehabilitation Technologies for Post-Stroke Patients

**Authors:** Hongbei Meng, Zihe Zhao, Shangru Li, Shengbo Wang, Jiacheng Wang, Canxi Yang, Chenyu Tang, Xuhang Chen, Xiaoxue Zhai, Yu Pan, Arokia Nathan, Peter Smielewski, Luigi G. Occhipinti, Shuo Gao

PMC · DOI: 10.3390/bios16010020 · Biosensors · 2025-12-25

## TL;DR

This review explores how active rehabilitation technologies can help stroke patients recover by leveraging neuroplasticity and real-time feedback.

## Contribution

The paper provides a comprehensive overview of recent advances in active rehabilitation for stroke recovery, focusing on intent detection and personalized treatment.

## Key findings

- Active rehabilitation enhances patient engagement and improves recovery outcomes through real-time intent detection.
- Cross-domain approaches enable comprehensive treatment tailored to different stages of stroke recovery.
- Emerging technologies offer optimized rehabilitation techniques for better functional recovery.

## Abstract

Neuroplasticity-based active movement opens an avenue for functional recovery in post-stroke patients. Active rehabilitation techniques have attracted wide attention based on their abilities to enhance patient involvement, facilitate precise personalized intervention, and provide comprehensive treatment via cross-domain approaches. Emerging evidence suggests that active rehabilitation methods can respond to patients’ motor intentions in real-time and significantly increase motivation and engagement, leading to efficient utilization of critical recovery windows and better rehabilitation outcomes. In this review, we focus on the physiological basis of active rehabilitation, including mechanisms of neuroplasticity, and discuss recent advances in intent detection and feedback devices. We also examine treatment options for different stages of stroke recovery, providing a comprehensive reference for engineers to design optimized rehabilitation techniques and for clinicians to select appropriate rehabilitation protocols. These developments create new opportunities to improve the lives of stroke patients and offer greater hope for their recovery.

## Linked entities

- **Diseases:** stroke (MONDO:0005098)

## Full-text entities

- **Diseases:** Post-Stroke (MESH:D020521)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

289 references — full list in the complete paper: https://tomesphere.com/paper/PMC12839297/full.md

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Source: https://tomesphere.com/paper/PMC12839297