# Local Diagnostic Reference Levels for Intracranial Aneurysm Coil-Only Embolization Using a Low-Dose Technique

**Authors:** Mariusz Sowa, Joanna Sowa, Kamil Węglarz, Maciej Budzanowski

PMC · DOI: 10.3390/biomedicines14010233 · Biomedicines · 2026-01-21

## TL;DR

This study establishes local radiation dose benchmarks for a low-dose technique used in treating brain aneurysms with coils, showing lower exposure compared to published values.

## Contribution

The paper introduces local diagnostic reference levels for a low-dose coil-only embolization technique in neurointerventional procedures.

## Key findings

- P75 DAP was 22.4 Gy·cm2, significantly lower than the literature range of 123–272.8 Gy·cm2.
- P75 fluoroscopy time was 18 min 56 s, with P50 at 13 min 25 s.
- The study's dose metrics fell within the lower range of published values for similar procedures.

## Abstract

Background/Objectives: Optimizing routine neurointerventional workflow and minimizing exposure to ionizing radiation during coil-only endovascular treatment of intracranial aneurysms depend on operator experience, reduced frame rates during both fluoroscopy and digital subtraction angiography (DSA), and the use of advanced angiographic systems. The low-dose protocol implemented in this study used the lowest available fluoroscopy frame rate (3.125 frames per second [fps]) and a nominal acquisition rate of 2 fps (actual = 2.45 fps) for DSA, three-dimensional (3D) rotational angiography, two-dimensional (2D)/3D mapping, and roadmapping. Methods: This retrospective analysis encompassed 245 coil-only procedures performed at a single tertiary center from 2018 to 2024. Data collected for each procedure included dose-area product (DAP), reference air kerma (Ka,r), fluoroscopy time (FT), and the total number of DSA frames. Local diagnostic reference levels (DRLs; 75th percentile [P75]) and typical values (50th percentile [P50]) were determined and descriptively compared with values reported in the literature. Results: The P75 values, representing DRLs, were 22.4 Gy·cm2 for DAP (literature range, 123–272.8 Gy·cm2), 268 mGy for Ka,r (1171–4240 mGy), 18 min 56 s for FT, and 285 DSA frames. The P50 values were 13.8 Gy·cm2 for DAP (78.7–179.0 Gy·cm2), 196 mGy for Ka,r (801–2804 mGy), 13 min 25 s for FT, and 208 DSA frames. Conclusions: In this single-center cohort, dose metrics for coil-only intracranial aneurysm treatment were within the lower range of published values. Cross-study comparisons are descriptive and require cautious interpretation. The proposed local DRLs may support quality assurance, dose optimization, and patient safety in comparable clinical settings. Further multi-center and multi-operator studies are warranted to evaluate transferability and applicability beyond coil-only procedures.

## Full-text entities

- **Diseases:** Intracranial Aneurysm (MESH:D002532)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

10 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12838866/full.md

## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12838866/full.md

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Source: https://tomesphere.com/paper/PMC12838866