# Development and Psychometric Validation of the Cyprus Aphasia Screening Test (CAST)

**Authors:** Marina Charalambous, Phivos Phylactou, Maria Kambanaros

PMC · DOI: 10.3390/brainsci16010032 · Brain Sciences · 2025-12-25

## TL;DR

The Cyprus Aphasia Screening Test (CAST) is a reliable and efficient tool developed to detect aphasia in Greek-speaking stroke patients in Cyprus.

## Contribution

CAST is the first standardized and validated aphasia screening tool for Greek-speaking populations in Cyprus.

## Key findings

- CAST showed excellent internal consistency, test–retest, and interrater reliability.
- The tool demonstrated strong diagnostic accuracy with an AUC of 0.97 and a cut-off score of 36/40.
- CAST correlates significantly with the Greek version of the Boston Diagnostic Aphasia Examination.

## Abstract

Background/Objectives: Aphasia screening tools help healthcare professionals detect aphasia after a stroke. To date, there is no standardized and validated aphasia screening tool available for use in Cyprus. The Cyprus Aphasia Screening Test (CAST) is a newly developed tool for detecting post-stroke aphasia. This study aims to present the main characteristics of the CAST and evaluate its psychometric properties and diagnostic accuracy. Methods: A cross-sectional study was conducted, involving 99 participants divided into three groups as follows: 43 people with stroke-aphasia, 21 with strokes but without aphasia, and 35 healthy controls. Results: The CAST demonstrated excellent internal consistency (Cronbach’s α > 0.967), high test–retest (ICC ≥ 0.983) and interrater (ICC = 0.979) reliability, and verified known-groups validity (p< 0.001). A significant correlation between the total scores of the CAST and the Greek version of the Boston Diagnostic Aphasia Examination (Short Form) confirmed a linear relationship across the two measures (p < 0.001). A ROC curve analysis (AUC = 0.97) identified 36/40 as the cut-off for detecting aphasia. Conclusions: The CAST is a reliable, clinician-administered aphasia screening tool with strong psychometric properties. It is designed to identify post-stroke aphasia and distinguish between stroke patients with and without aphasia. It consists of 10 subtests that assess both language comprehension and production. The CAST is designed for easy scoring and requires minimal equipment, making it well-suited for quick and efficient administration at the bedside. The CAST represents a step forward in aphasia screening for Greek-speaking populations in Cyprus.

## Linked entities

- **Diseases:** aphasia (MONDO:0000598), stroke (MONDO:0005098)

## Full-text entities

- **Diseases:** stroke (MESH:D020521), Aphasia (MESH:D001037)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

41 references — full list in the complete paper: https://tomesphere.com/paper/PMC12838679/full.md

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Source: https://tomesphere.com/paper/PMC12838679