# Is Sex an Underrated Risk for Relapse in Substance Use Disorders?

**Authors:** Annette Bohn, Niels Graf, Norbert Scherbaum, Daniel Deimel, Henrike Schecke

PMC · DOI: 10.3390/brainsci16010071 · Brain Sciences · 2026-01-03

## TL;DR

The study explores how sexual activity influences relapse in substance use disorders, finding that it is a significant risk, especially for stimulant users.

## Contribution

This study highlights the under-recognized role of sexual activity as a relapse risk in substance use disorder rehabilitation.

## Key findings

- 55% of men and 63% of women reported sexualized substance use.
- Homosexual men reported higher rates of sexualized substance use compared to heterosexual men.
- Stimulant users are more likely to report sexualized substance use than alcohol or sedative users.

## Abstract

Background: Sexualized substance use (SSU) describes the use of psychotropic substances in the context of sexual activity. Less is known about the role of sexualized substance use among individuals with substance use disorders (SUD) and its effect on the course of the disorder, e.g., regarding relapses after abstinence. Methods: A convenience sample of individuals undergoing SUD rehabilitation in Germany was surveyed. A questionnaire asked about SSU, sex as a risk factor for relapse, and the importance of sexuality in treatment. Results: N = 490 (30.1% female) participated; 55% of men and 63% of women reported SSU, and 56.5% of heterosexual and 82.9% of homosexual men reported SSU (p < 0.017; r = 0.20). Stimulant users are more likely to report SSU than alcohol (p < 0.001) and sedative users (p < 0.001; r = 0.296 and r = 0.261). Furthermore, 15% of women and 18% of men consider sexual activity a risk factor for relapse; homosexual men (65%) consider it significantly more often than heterosexual men (14%), while 41.2% of heterosexual women and 55% of homosexual women consider it a factor. Additionally, 27.4% of heterosexual and 69.4% identified sexuality as an important topic for therapy, while 19.8% of heterosexual women, 30% of homosexual women, 13.5% of heterosexual men, and 47.2% of homosexual men reported that sexuality had been addressed in their therapy. Conclusions: SSU was reported by individuals with a SUD who were undergoing rehabilitation treatment. Furthermore, patients consider sexual activity as a potential risk factor for relapse, with this being particularly the case for stimulant users. The topic of sexuality is highly important for patients and should, therefore, be given greater consideration in therapy in the future.

## Full-text entities

- **Diseases:** Sexualized (MESH:D050035), SUD (MESH:D019966)
- **Chemicals:** alcohol (MESH:D000438), psychotropic substances (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12838658/full.md

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Source: https://tomesphere.com/paper/PMC12838658