# Nanoaggregate-Based Innovative Electrochemiluminescence Sensors for Foodborne Contaminant Analysis

**Authors:** Tingting Han, Jinyang Zhuang, Yueling Lu, Jianhong Xu, Jun-Jie Zhu

PMC · DOI: 10.3390/bios16010006 · Biosensors · 2025-12-22

## TL;DR

This review discusses new electrochemiluminescence sensors using nanoaggregates to detect food contaminants, aiming to improve food safety and public health.

## Contribution

The paper provides a comprehensive review of nanoaggregate-based ECL sensors for food contaminants, an area not yet fully covered in literature.

## Key findings

- Nanoaggregate-based ECL sensors offer high sensitivity and low background signals for contaminant detection.
- Recent advances in ECL sensor fundamentals and applications are summarized for food safety monitoring.
- Challenges and future trends in next-generation ECL sensors are identified.

## Abstract

The pervasive presence of foodborne contaminants in foods poses a significant global threat, contributing to various foodborne diseases and food safety issues. Therefore, developing rapid, sensitive, and universal detection methods for them is essential to ensure public health and food safety. Electrochemiluminescence (ECL) sensors, particularly those incorporating innovative nanoaggregates, have been widely used to detect related contaminant residues in foodstuffs owing to their superior sensitivity and low background signals. This review summarizes recent advances in nanoaggregate-based novel ECL sensors for detecting a wide range of contaminants, with emphasis on their fundamentals and representative applications. This area has not yet been comprehensively covered in the existing literature. The current challenges and emerging trends for next-generation ECL sensors based on nanoaggregates in food safety monitoring are also discussed.

## Full-text entities

- **Diseases:** foodborne diseases (MESH:D005517)

## Full text

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## Figures

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## References

128 references — full list in the complete paper: https://tomesphere.com/paper/PMC12838546/full.md

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Source: https://tomesphere.com/paper/PMC12838546