# Complex Dermatological Manifestations of Poorly Controlled Diabetes: A Case of Acquired Ichthyosis

## TL;DR

A 67-year-old man with poorly controlled diabetes developed acquired ichthyosis, a rare skin condition, which improved with treatment and diabetes management.

## Contribution

This case highlights the association between poorly controlled diabetes and acquired ichthyosis, emphasizing the need for comprehensive evaluation.

## Key findings

- Acquired ichthyosis was confirmed in a patient with poorly controlled diabetes mellitus.
- Treatment with moisturizers, corticosteroids, and optimized diabetes management led to clinical improvement.
- The case underscores the importance of systemic workup to identify underlying conditions in acquired ichthyosis.

## Abstract

Acquired ichthyosis (AI) is a rare dermatological disorder characterized by dry, scaly skin. This case involves a 67‐year‐old Hispanic male with poorly controlled diabetes mellitus (DM) who presented with generalized dryness and itchiness after diabetic ketoacidosis. Examination revealed polygonal scales with erythema, and biopsy confirmed AI. Laboratory tests showed elevated glucose, dyslipidemia, hyponatremia, hyperkalemia, and Stage IIIb chronic kidney disease. Treatment included moisturizers, antihistamines, antifungal shampoo, topical corticosteroids, tacrolimus, and optimized DM management, leading to improvement. AI is often linked to systemic conditions like malignancy, autoimmune diseases, infections, and certain medications. Diagnosis is clinical and biopsy‐supported, requiring a systemic workup to identify underlying causes. Poorly controlled DM was significant in this case, highlighting the importance of comprehensive assessment. Early recognition and understanding of AI’s association with DM can optimize treatment and reduce morbidity.