# Effect of Mindful Hypnotherapy on Psychological Distress: A Systematic Review and Meta-Analysis

**Authors:** Victor Julián Padilla, Vanessa Muñiz, Katherine Scheffrahn, Gary Elkins

PMC · DOI: 10.3390/bs16010107 · Behavioral Sciences · 2026-01-13

## TL;DR

This study finds that mindful hypnotherapy significantly reduces psychological distress and increases mindfulness in adults.

## Contribution

The paper provides the first meta-analysis on the effectiveness of mindful hypnotherapy for psychological distress and mindfulness.

## Key findings

- Mindful hypnotherapy significantly reduces psychological distress compared to waitlist and active control groups.
- It also significantly increases mindfulness levels in participants.
- The study highlights the need for further research on diverse populations and clinical conditions.

## Abstract

Mindful hypnotherapy is an intervention that integrates hypnotic induction and direct suggestions (hypnosis) to increase mindfulness and reduce distress. In the present study, a systematic review and meta-analysis were conducted to investigate the effects of mindful hypnotherapy on psychological distress and mindfulness in adults. Further, the study evaluated the methodological quality of the included studies. A total of five publications of randomized controlled trials were identified. This meta-analysis found that, when compared to both waitlist and active control groups, mindful hypnotherapy had a large effect on the reduction in psychological distress (Hedges’ g = 0.61, 95% CI [0.10, 1.12], z = 2.36, p = 0.0188) and stress (Hedges’ g = 0.75, 95% CI [0.34, 1.16]; z = 3.58, p = 0.0003). Further, results also found mindful hypnotherapy had a large effect on increasing mindfulness (Hedges’ g = 1.38, SE = 0.28; 95% CI [0.83, 1.92]; z = 4.9146, p < 0.001). Recommendations include conducting research examining mindful hypnotherapy in a wider range of clinical problems (i.e., generalized anxiety disorder, depression, post-traumatic stress). In addition, clinical trials of mindful hypnotherapy should include active controls and measures of hypnotizability. Further research is also needed with diverse populations.

## Linked entities

- **Diseases:** generalized anxiety disorder (MONDO:0001942), depression (MONDO:0002050)

## Full-text entities

- **Diseases:** anxiety disorder (MESH:D001008), depression (MESH:D003866), post-traumatic stress (MESH:D013313)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12837898/full.md

## References

44 references — full list in the complete paper: https://tomesphere.com/paper/PMC12837898/full.md

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Source: https://tomesphere.com/paper/PMC12837898