# The ESMO-Magnitude of Clinical Benefit Scale (ESMO-MCBS) visualisation: picturing the evidence of clinical benefit of clinical trial data

**Authors:** C.G. Urzua-Traslavina, N.J. Latino, M. Galotti, N.I. Cherny, S.F. Oosting, E.G.E. de Vries, R.S.N. Fehrmann

PMC · DOI: 10.1016/j.esmorw.2025.100171 · ESMO Real World Data and Digital Oncology · 2025-08-26

## TL;DR

This paper introduces a visual tool to help understand cancer treatment benefits, making it easier for experts to use and interpret clinical trial data.

## Contribution

A user-friendly visualization of the ESMO-MCBS scores was developed and validated for broader understanding.

## Key findings

- A two-panel visualization was created to represent ESMO-MCBS scoring steps.
- Over 80% of experts found the final visualization accessible and effective.
- The visualizations were integrated into public ESMO-MCBS Scorecards.

## Abstract

Choosing the right cancer treatment is crucial for patients and health care professionals, while health care systems must allocate resources efficiently. The European Society for Medical Oncology-Magnitude of Clinical Benefit Scale (ESMO-MCBS) assists decision making by assessing the clinical benefit of anticancer medications. ESMO developed and field-tested a visualisation of the ESMO-MCBS scores to increase its user-friendliness and effectiveness.

An expert panel iteratively designed and internally reviewed a prototype of the visualisation, then refined it through field-testing. A survey was conducted concurrently with the field-testing to evaluate the understandability of the visualisation. Field-testing materials and survey questions were made accessible to the public on the ESMO website and promoted at the ESMO Congress 2019 through ESMO social media platforms. The insights gathered from all the feedback were instrumental in refining the design. Subsequently, a conclusive survey was deployed during the ESMO Congress 2023 to assess the final version of the visualisation.

A two-panel visualisation was developed to reflect the steps of the ESMO-MCBS scoring procedure. Field-testing included visualisations for 121 studies, each based on their ESMO-MCBS scores. Feedback from the survey (n = 56 experts) indicated that oncology-related professions and statisticians, as well as respondents with previous knowledge of the ESMO-MCBS, showed a sufficient understanding of the visualisations while indicating areas to improve. Incorporating the survey’s feedback, the revised visualisations were then integrated into the publicly available ESMO-MCBS Scorecards, and a final survey (n = 118 experts) was conducted to evaluate these revisions. More than 80% of the respondents reported the visualisation to be accessible and effective at communicating the score.

The visualisations offer a visual understanding of the ESMO-MCBS scores by enhancing user-friendliness and understandability.

•Choosing the right cancer drug is vital for patients, doctors, and regulators.•Visualisation aids decisions and boosts transparency and accountability.•An ESMO-MCBS visual tool was tested and refined for broad understanding.•All ESMO-MCBS visuals and scorecards are available on the ESMO website.

Choosing the right cancer drug is vital for patients, doctors, and regulators.

Visualisation aids decisions and boosts transparency and accountability.

An ESMO-MCBS visual tool was tested and refined for broad understanding.

All ESMO-MCBS visuals and scorecards are available on the ESMO website.

## Full-text entities

- **Diseases:** cancer (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12836693/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12836693/full.md

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Source: https://tomesphere.com/paper/PMC12836693