# Role of Damage Control Surgery in Severe Liver Trauma: A Systematic Review of Mortality, Morbidity, and ICU Stay

**Authors:** Beshr Mosa Basha, Ammar M Eskander, Rana M Haris, Ahmad Hamdan, Shashwat Shetty, Yousif Osman, Aliaa Alkhazendar, Ifrah Saleem

PMC · DOI: 10.7759/cureus.100222 · 2025-12-27

## TL;DR

This review examines how damage control surgery improves survival and reduces ICU stays in patients with severe liver injuries.

## Contribution

The study systematically evaluates DCS effectiveness in severe liver trauma, highlighting optimal timing for re-laparotomy.

## Key findings

- Damage control surgery improves short-term survival in critically unstable patients with severe liver trauma.
- Early re-laparotomy within 24-48 hours reduces ICU stay and postoperative complications.
- Mortality remains high due to initial physiological instability and associated injuries.

## Abstract

This systematic review evaluates the role of damage control surgery (DCS) in managing severe hepatic trauma (AAST grade III-V), focusing on mortality, morbidity, and ICU stay. A comprehensive search of PubMed, Embase, Scopus, and the Cochrane Library identified six studies with a combined sample size of 1,497 patients, analyzed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. DCS comprising perihepatic packing, temporary abdominal closure, and staged re-laparotomy was shown to improve short-term survival by rapidly controlling hemorrhage and stabilizing physiology in critically unstable patients. Evidence indicated that early re-laparotomy (within 24-48 hours) reduced ICU stay and postoperative complications compared with delayed re-exploration. Despite improved outcomes, mortality remained influenced by initial physiological instability and associated injuries. Most studies presented a moderate risk of bias due to retrospective designs and heterogeneity in protocols. Overall, DCS remains a cornerstone in the management of severe liver trauma, and future multicenter prospective studies are needed to refine operative timing, standardize protocols, and optimize patient outcomes.

## Full-text entities

- **Diseases:** hemorrhage (MESH:D006470), Liver Trauma (MESH:D017093), AAST grade III-V (MESH:D001254), Damage (MESH:D020263), postoperative complications (MESH:D011183), hepatic trauma (MESH:D014947)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12835568/full.md

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Source: https://tomesphere.com/paper/PMC12835568