The V‐Shaped Hamilton Receptors: A Paradigmatic Multipurpose Scaffold
Shafieq Ahmad Wagay, Rashid Ali
TL;DR
This review explores the development and applications of Hamilton-type receptors in molecular recognition and supramolecular chemistry.
Contribution
This is the first comprehensive review detailing the synthesis, recognition, and applications of Hamilton-type receptors.
Findings
Hamilton receptors have been applied to sense barbiturates, anions, amino acids, and drug molecules.
They are used in rotaxanes and supramolecular catalysis, showing broad functional potential.
The review outlines future directions for functionalized Hamilton-type receptors.
Abstract
Sensors are devices that can detect and enumerate the physical and/or chemical aspects in real time. The generation of novel sensory materials for sensing/recognition of chemical entities are significant for protecting both the environment and humanity. This review article reveals the achievements made in the designed synthesis and molecular recognition of Hamilton‐type receptors since first report by Hamilton in 1988 to till date. This is the first elaborative manuscript in which Hamilton receptor is being exposed in detail. This manuscript is divided into three parts, in which the first portion highlights the importance and urgency of molecular recognition along with the historic background of Hamilton receptor. Whereas, the middle section discloses potential applications of Hamilton receptor in sensing and recognition of barbiturate molecules, anions, neutral molecules, drug…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsSupramolecular Chemistry and Complexes · Molecular Sensors and Ion Detection · Synthesis and Properties of Aromatic Compounds