# Multi-disciplinary diagnosis and management of verrucous venous malformation of the right knee: a case report

**Authors:** Varun H, Bhushan Madke, Prerit Sharma, Adarshlata Singh, Anurag Mittal, Vedashree Vedprakash Tiwari

PMC · DOI: 10.3389/fradi.2025.1686404 · 2026-01-13

## TL;DR

A 10-year-old boy with a rare vascular malformation on his knee was diagnosed and treated using multiple methods, showing the value of a team-based approach.

## Contribution

This case report presents a multidisciplinary diagnostic and treatment approach for a rare VVM in a pediatric patient.

## Key findings

- The lesion was diagnosed as a VVM through clinical, radiologic, and histopathological evaluation.
- Percutaneous sclerotherapy was effective in reducing the lesion size.
- Multidisciplinary care improved clinical outcomes for the patient.

## Abstract

Verrucous Venous Malformations (VVMs) are a rare subtype of Congenital Vascular Malformations (CVMs) characterised by a hyperkeratotic, verrucous surface. We present the case of a ten-year-old male with a VVM localised to the right knee, which presented as a gradually enlarging, asymptomatic lesion since birth. A comprehensive, multi-modality diagnostic workup was performed, including thorough clinical evaluation, dermoscopy, radiologic imaging (Plain radiograph, colour Doppler ultrasonography and magnetic resonance imaging) and histopathological analysis with hematoxylin and eosin staining, along with immunohistochemical staining for CD-34. The lesion exhibited characteristic features consistent with VVM. The patient was managed by percutaneous sclerotherapy to reduce lesion size. This case highlights the importance of a multidisciplinary strategy in the diagnosis and management of VVMs to improve clinical outcomes.

## Full-text entities

- **Genes:** CD34 (CD34 molecule) [NCBI Gene 947]
- **Diseases:** VVMs (MESH:D018289), CVMs (MESH:D054079)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12834784/full.md

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Source: https://tomesphere.com/paper/PMC12834784