Retraction: Arctigenin inhibits the progression of colorectal cancer through epithelial-mesenchymal transition via PI3K/Akt/mTOR signaling pathway

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Following the publication of this article [1], concerns were raised regarding Figs 3, 4, and 6–8. Specifically:

Furthermore, PLOS noted that details on the solvent used for arctigenin and critical controls were not included for the reported in vitro and in vivo experiments where the effect of arctigenin was evaluated.

The corresponding author, PF, stated that errors were made when the image data were uploaded.

In light of the extent of the above unresolved concerns that question the reliability and integrity of the results presented in [1], the PLOS One Editors retract this article.

Since the publication of [1], Reference 5 [4] has been retracted [5].

PF responded but expressed neither agreement nor disagreement with the editorial decision. XFC, PGL, NS, XSL, RKH, and LXZ either did not respond directly or could not be reached.