This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
Retraction: Investigating new bilosomes for ex vivo skin deposition, in vitro characterization, and transdermal delivery of nimodipine
Ananda Kumar Chettupalli, Sarad Pawar Naik Bukke, Godswill James Udom, Tenpattinam Shanmugam Saraswathi, Shaik Abdul Rahaman, Sachchida Nand Rai, Marati Kavitha, Narender Boggula, Narayana Goruntla, Tadele Mekuriya Yadesa, Hope Onohuean

TL;DR
This retraction notice addresses a paper on developing bilosomes for delivering nimodipine through the skin.
Contribution
The paper was retracted, indicating potential issues with its findings or methodology.
Findings
The paper was retracted by the authors or publisher.
It originally aimed to investigate bilosomes for transdermal drug delivery of nimodipine.
Abstract
Retraction of ‘Investigating new bilosomes for ex vivo skin deposition, in vitro characterization, and transdermal delivery of nimodipine’ by Ananda Kumar Chettupalli et al., Nanoscale Adv., 2024, Accepted Manuscript, https://doi.org/10.1039/d4na00510d.
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Taxonomy
TopicsAdvancements in Transdermal Drug Delivery · Advanced Drug Delivery Systems · Graphene and Nanomaterials Applications
The Royal Society of Chemistry hereby wholly retracts this Nanoscale Advances article due to concerns with the reliability of the data.
Fig. 11a of this article was first published in ref. 1 and reported as another compound.
Fig. 14 of this article was first published in ref. 2 and reported as another material.
In addition, following the publication of this article, a Royal Society of Chemistry journal received a submission with several shared co-authors that contained a piece of overlapping data with this published article.
We consulted an independent expert who asked for additional data from the TEM and histopathological experiments. The authors were not able to provide any additional data from their experiments.
Given the significance of these concerns, the Editor has lost confidence that the findings presented in this paper are reliable.
All authors were informed of the decision to retract this article. Ananda Kumar Chettupalli and Sarad Pawar Naik Bukke disagreed with the decision. Sachchida Nand Rai acknowledged the decision but did not agree nor disagree, and the other authors did not respond to any correspondence.
Signed: Jeremy Allen, Executive Editor, Nanoscale Advances
Date: 16th January 2026
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Unnisa A. Chettupalli A. K. Alazragi R. S. Alelwani W. Bannunah A. M. Barnawi J. Amarachinta P. R. Jandrajupalli S. B. Elamine B. A. Mohamed O. A. Hussain T. Pharmaceuticals 202316115110.3390/ph 1608115137631066 PMC 10458271 · doi ↗ · pubmed ↗
- 2Moideen Muthu Mohamed J. Khan B. A Rajendran V. El-Sherbiny M. Othman G. Bashir Ahmed Hussamuldin A. Hamed Al-Serwi R. Saudi Pharm. J.2022301603161110.1016/j.jsps.2022.09.00336465850 PMC 9715949 · doi ↗ · pubmed ↗
