# The complete chloroplast genome and phylogenetic analysis of Pterospermum heterophyllum (Malvaceae)

**Authors:** Yihong Luo, Yang Ni, Jiahua Chen, Guoan Shen, Lichai Yuan

PMC · DOI: 10.1080/23802359.2026.2619279 · Mitochondrial DNA. Part B, Resources · 2026-01-24

## TL;DR

This paper reports the complete chloroplast genome of Pterospermum heterophyllum and its phylogenetic relationships with related species.

## Contribution

The study provides a new chloroplast genome sequence and phylogenetic insights for Pterospermum heterophyllum.

## Key findings

- The chloroplast genome is 162,857 bp with typical quadripartite structure and 130 annotated genes.
- The infA gene has a large 3′ deletion truncating its coding sequence.
- Phylogenetic analysis shows P. heterophyllum is closely related to P. kingtungense and P. truncatolobatum.

## Abstract

Pterospermum heterophyllum Hance (1868), a member of the Malvaceae family, is widely distributed across southwestern and southeastern China and has been traditionally used in folk medicine to treat rheumatoid arthritis and inflammation-related diseases. The circular genome is 162,857 bp long and exhibits a typical quadripartite structure, consisting of an LSC (91,356 bp), SSC (20,567 bp), and two IRs (25,467 bp each). A total of 130 genes were annotated. The multiple sequence alignment revealed that infA gene contained a large 3′ deletion truncating the coding sequence. Phylogenetic analysis revealed that P. heterophyllum is closely related to P. kingtungense and P. truncatolobatum.

## Linked entities

- **Genes:** IFNA17 (interferon alpha 17) [NCBI Gene 3451]
- **Diseases:** rheumatoid arthritis (MONDO:0008383)
- **Species:** Pterospermum heterophyllum (taxon 190904), Malvaceae (taxon 3629)

## Full-text entities

- **Genes:** IFNA17 (interferon alpha 17) [NCBI Gene 3451] {aka IFN-alphaI, IFNA, INFA, LEIF2C1}
- **Diseases:** inflammation (MESH:D007249), rheumatoid arthritis (MESH:D001172)
- **Species:** Pterospermum heterophyllum (species) [taxon 190904], Pterospermum truncatolobatum (species) [taxon 2303458], Pterospermum kingtungense (species) [taxon 1686260]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12833906/full.md

## References

36 references — full list in the complete paper: https://tomesphere.com/paper/PMC12833906/full.md

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Source: https://tomesphere.com/paper/PMC12833906