# First Reported Case of Simultaneous Transjugular Tricuspid Valve-in-Ring and Pulmonary Valve-in-Valve Implantation

**Authors:** Mohamed Al Nasef, Bandar Al Shehri, Ahmed Al Zahrani, Merna Atiyah, Saria Mansour Ahmed, Khalid Al Najashi

PMC · DOI: 10.1016/j.jaccas.2025.105931 · JACC Case Reports · 2025-11-04

## TL;DR

A 46-year-old man with repaired tetralogy of Fallot underwent a novel dual transjugular valve replacement to treat severe right heart failure.

## Contribution

This is the first reported case of simultaneous transjugular tricuspid valve-in-ring and pulmonary valve-in-valve implantation.

## Key findings

- Transjugular valve implantation resolved severe tricuspid and pulmonary dysfunction in a patient with complex anatomy.
- The procedure avoided high-risk surgery and transfemoral access due to anatomical constraints.
- Meticulous imaging and planning enabled successful dual valve replacement.

## Abstract

Patients with repaired tetralogy of Fallot often require reinterventions for right-sided valve dysfunction. Surgical reoperations carry high morbidity, making transcatheter valve-in-valve and valve-in-ring procedures valuable alternatives.

A 46-year-old man with repaired tetralogy of Fallot, prior tricuspid annuloplasty, pulmonary bioprosthesis, and transcatheter pacemaker presented with advanced right heart failure. Imaging showed massive right atrial enlargement, severe tricuspid stenosis/regurgitation, pulmonary dysfunction, and indwelling leads, precluding transfemoral access. Repeat surgery was prohibitive; thus, simultaneous transcatheter intervention was pursued. Via a transjugular approach, Edwards Sapien valves were implanted in both the tricuspid and pulmonary positions, with complete resolution of regurgitation.

This case illustrates the feasibility of dual transjugular right-sided valve replacement in complex congenital heart disease. Meticulous imaging and planning allowed safe navigation of anatomical challenges.

A combined transjugular-approach valve-in-ring and valve-in-valve procedure can provide an effective alternative when surgery is prohibitive.

## Linked entities

- **Diseases:** tetralogy of Fallot (MONDO:0008542), tricuspid stenosis (MONDO:0005997)

## Full-text entities

- **Diseases:** congenital heart disease (MESH:D006330), atrial enlargement (MESH:D006332), tetralogy of Fallot (MESH:D013771), right heart failure (MESH:D006333), tricuspid stenosis/regurgitation (MESH:D014264), pulmonary dysfunction (MESH:D011660), valve dysfunction (MESH:D006349)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12833654/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12833654/full.md

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Source: https://tomesphere.com/paper/PMC12833654