# Laser acupuncture in the treatment of musculoskeletal disorders: systematic review and meta-analysis

**Authors:** Sooyoon Lee, Euijin Son, Yubin Bae, Hyo-Jin Kim, Seunghoon Lee, Jongwoo Kim, Jin-Gyun Kim, Younbyoung Chae, In-soo Jang, In-Seon Lee

PMC · DOI: 10.3389/fneur.2025.1672380 · Frontiers in Neurology · 2026-01-12

## TL;DR

This study reviews clinical evidence for laser acupuncture in treating musculoskeletal disorders and highlights inconsistencies in reporting laser parameters.

## Contribution

The paper provides a systematic review and meta-analysis of laser acupuncture protocols and outcomes for musculoskeletal disorders.

## Key findings

- Many studies failed to distinguish laser acupuncture from low-intensity laser therapy and lacked detailed laser parameter descriptions.
- Inconsistent reporting of laser parameters complicates understanding of treatment effects.
- The study identifies a need for standardized protocols and new guidelines for laser acupuncture research.

## Abstract

Laser acupuncture, which involves laser stimulation of acupuncture points including traditional acupoints, Ashi, and trigger points, combines the benefits of photobiomodulation and acupuncture effects. Evidence from randomized controlled trials and systematic reviews suggests that laser acupuncture and lowlevel laser therapy can reduce pain, improve functional outcomes, and decrease disability in patients with musculoskeletal disorders. However, the field is relatively new and involves complex mechanisms, leading to varied opinions on its benefits. Standardized, condition-specific stimulation protocols for laser acupuncture have not yet been established, as existing studies report heterogeneous parameters and lack consistent reporting practices. One major challenge in validating the clinical effects of laser acupuncture is the inconsistency in nomenclature and the lack of consensus on critical parameters and clinical guidelines.

This study aims to provide a descriptive synthesis of existing clinical evidence on laser acupuncture for musculoskeletal disorders and to describe the range and reporting quality of laser-related parameters used in these studies. In doing so, it offers a basis for future efforts to harmonize reporting and clinical practice.

We reviewed 28 randomized controlled trials focused on laser acupuncture for musculoskeletal disorders and conducted a meta-analysis on 14 of these studies. Key variables included laser type, wavelength, mode, duration, frequency, irradiance, power density, area, density/probe, total exposure energy, exposure time, treatment frequency and duration, and clinical outcomes.

Our findings revealed that many studies did not distinguish terms like Low-Intensity Laser Therapy from laser acupuncture, and lacked detailed descriptions of laser parameters, which could affect outcomes. The complexity of laser acupuncture mechanisms and its diverse variables make it challenging to understand which factors impact therapeutic effects.

Therefore, it is crucial to detail all possible variables in future research to clarify the relationship between dosage and treatment effects. Finally, due to challenges in applying current guidelines, new guidelines specifically for laser acupuncture research may be necessary.

https://osf.io/es9k2.

## Full-text entities

- **Diseases:** pain (MESH:D010146), musculoskeletal disorders (MESH:D009140)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12833518/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12833518/full.md

## References

56 references — full list in the complete paper: https://tomesphere.com/paper/PMC12833518/full.md

---
Source: https://tomesphere.com/paper/PMC12833518