Correction: Multimorbidity patterns and cognitive frailty in adults aged over 50 years: China perspective
Jiehua Zhu, Chenxi Ren, Tingjun Hu, Jun Jin, Qihao Guo

Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsChronic Disease Management Strategies · Frailty in Older Adults · Machine Learning in Healthcare
The citations for Lv et al. (2025) (37), Aprahamian et al. (2020) (38), and Grande et al. (2021) (39) were not correctly formatted in the article.
The citations have now been correctly formatted and inserted in the section Discussion, paragraphs 4 and 5 and added to the reference list.
The corrected paragraphs should read:
“The association between CCVD and SG, SCD, or cognitive frailty is well supported by prior research, but our study advances this understanding by focusing on their co-occurrence in SCD-SG, MCI-SG. Notably, while the rising prevalence and mortality of cardiovascular disease (CVD) in China underscore the clinical relevance of these links (29), prior work—including a recent study (37) has primarily focused on aggregate multimorbidity burden or isolated cognitive or gait outcomes rather than their combined presentation in preclinical stages.”
“Some studies reported that cardiovascular and metabolic multimorbidity correlates with incident cognitive frailty in older adults, emphasizing shared inflammatory pathways (38, 39). Our findings align with this mechanistic framework: elevated IL-6 and C-reactive protein have been linked to SG (30), reduced gray matter and hippocampal volume (31, 32)—structures critical for cognition and gait regulation—and subsequent cognitive decline (33). However, we extend this work by demonstrating that these inflammatory pathways also intersect with gender-specific comorbidities in preclinical AD subgroups, a gap not addressed in prior research.”
The figure citations incorrectly cited only the part figures instead of the whole figure. The citation “Figure 1A” should be edited to “Figure 1”; and the citation “Figure 2A” should be edited to “Figure 2”.
The original version of this article has been updated.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Lv J Huang F Shi Y. Association between multimorbidity and cognitive frailty among the elderly in China: the mediating effect of depressive symptoms. Exp Gerontol. (2025) 210:112864. doi: 10.1016/j.exger.2025.11286440816438 · doi ↗ · pubmed ↗
- 2Aprahamian I Mamoni RL Cervigne NK Augusto TM Romanini CV Petrella M . Design and protocol of the multimorbidity and mental health cohort study in frailty and aging (Mi Mi CS-FRAIL): unraveling the clinical and molecular associations between frailty, somatic disease burden and late life depression. BMC Psychiatry. (2020) 20:573. doi: 10.1186/s 12888-020-02963-933261579 PMC 7706060 · doi ↗ · pubmed ↗
- 3Grande G Marengoni A Vetrano DL Roso-Llorach A Rizzuto D Zucchelli A . Multimorbidity burden and dementia risk in older adults: The role of inflammation and genetics. Alzheimers Dement. (2021) 17:768–76. doi: 10.1002/alz.1223733403740 PMC 8247430 · doi ↗ · pubmed ↗
