# Repeat posterior fossa exploration and external neurolysis for recurrent trigeminal neuralgia following microvascular decompression

**Authors:** Zhong Liu, Jiao Xu, Ming-Liang Ren, Min-Hui Xu, Sha Chen, Xu-Zhi He, Xu-Hui Wang

PMC · DOI: 10.3389/fsurg.2025.1694389 · Frontiers in Surgery · 2026-01-12

## TL;DR

This study shows that re-exploring the posterior fossa and performing limited neurolysis can effectively treat trigeminal neuralgia that recurs after initial surgery.

## Contribution

The study demonstrates the effectiveness of repeat posterior fossa exploration and limited neurolysis in treating recurrent trigeminal neuralgia after microvascular decompression.

## Key findings

- 92% of patients experienced complete pain relief immediately after surgery.
- Teflon adhesion was found in 92% of patients during re-exploration.
- Limited neurolysis helped reduce complications like facial numbness.

## Abstract

Recurrence of trigeminal neuralgia (TN) after microvascular decompression (MVD) poses a challenge for neurosurgeons. This study aimed to investigate the effect of repeat posterior fossa exploration (RPFE) and external neurolysis for TN recurrence following MVD.

Totally, 38 TN patients who experienced recurrence after MVD were included. All patients underwent RPFE and limited neurolysis. The Barrow Neurological Institute Pain Intensity Scale were utilized to evaluate preoperative pain and postoperative outcomes.

The median follow-up period was 63.8 months (range: 5–112 months). Thirty-three out of the 38 patients achieved excellent outcomes, 4 had good outcomes, and 1 experienced failure. The rates of complete pain relief was 92% immediately post-surgery and 86.8% at the final follow-up. Re-exploration revealed Teflon adhesion in almost all patients (92%). Complications included new facial numbness (n = 5), temporary facial weakness (n = 3), hearing loss and tinnitus (n = 1), wound infection (n = 1), and postoperative hemorrhage (n = 1).

Teflon adhesion was frequently observed upon re-exploration. A substantial majority of TN patients experiencing recurrence post-MVD achieved positive outcomes via RPFE and neurolysis. Complications, particularly facial numbness attributed to premature excessive Teflon dislodgement, continue to pose challenges. However, limited neurolysis, have proven effective in minimizing these complications.

## Linked entities

- **Diseases:** trigeminal neuralgia (MONDO:0008599)

## Full-text entities

- **Diseases:** tinnitus (MESH:D014012), hemorrhage (MESH:D006470), hearing loss (MESH:D034381), TN (MESH:D014277), wound infection (MESH:D014946), numbness (MESH:D006987), weakness (MESH:D018908), Pain (MESH:D010146)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12833354/full.md

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Source: https://tomesphere.com/paper/PMC12833354