# Effects of sedative practices on grief in the spouse of a patient who has died of cancer. An international systematic review

**Authors:** Yasmine Chemrouk, Livia Sani, Marthe Ducos, Pascal Gauthier, Marie-Frédérique Bacqué

PMC · DOI: 10.3389/fpsyg.2025.1603194 · Frontiers in Psychology · 2026-01-12

## TL;DR

This paper reviews how sedative practices affect the grief of spouses whose partners died from cancer, highlighting a lack of research on the topic.

## Contribution

The novelty lies in identifying a research gap regarding the psychological impact of continuous deep sedation on bereaved spouses.

## Key findings

- No studies were found on the effects of continuous deep sedation on spousal grief.
- The absence of research may be due to the rarity or taboo nature of the practice.
- The paper calls for further investigation into the psychological consequences of sedative practices.

## Abstract

The spouse is the most at risk of developing psychological consequences following the loss of a partner (anxiety, depression, complicated grief) compared to other family caregivers. The principal aim of this study was to investigate the possible implications and bereavement process for those who have lost a spouse following a cancer diagnosis and the implementation of continuous deep sedation (CDS).

A scoping review was conducted according to the PRISMA protocol using the following databases: PubMed, Cochrane Library, Google Scholar, PsycInfo, Overview, PsycArticles, and PubPsych. The publication period used as a selection criterion was 2010–2023.

A total of 317 articles emerged from the keywords. However, the research studies focused exclusively on the practice of CDS, and the consequences of bereaved partners did not produce any results.

The absence of selected articles has revealed various reflections and questions. Is it possible that CDS and its effects on grief are not evaluated because the practice is infrequent? As perceived and symbolically associated with euthanasia, can this lead to moral conflicts where it is illegal, and therefore generate a taboo? Given the results of the following study and the role of the grieving partner, it is essential to conduct further research on this topic and to suggest it.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** cancer (MESH:D009369), anxiety (MESH:D001007), depression (MESH:D003866)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

83 references — full list in the complete paper: https://tomesphere.com/paper/PMC12833309/full.md

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Source: https://tomesphere.com/paper/PMC12833309