# A novel LNG-IUS suture fixation method utilizing the hysteroscopy cold knife system: nail-type anchoring suture

**Authors:** Duan Duan, Li He, Chengling Zhang, Qiannan Hou, Qinyan Cao, Ying Xiong

PMC · DOI: 10.3389/fmed.2025.1714366 · Frontiers in Medicine · 2026-01-12

## TL;DR

A new suture method for LNG-IUS devices is introduced to prevent displacement, offering better contraceptive and therapeutic outcomes.

## Contribution

The novel nail-type anchoring suture technique for LNG-IUS fixation is developed and validated clinically.

## Key findings

- The nail-type suture technique effectively secures LNG-IUS devices, reducing displacement risks.
- The method improves clinical outcomes and eliminates the need for hysteroscopic visualization during removal.
- It is particularly beneficial for patients with enlarged uterine cavities or a history of IUD displacement.

## Abstract

The levonorgestrel intrauterine system (LNG-IUS) may have its contraceptive or therapeutic efficacy compromised if displacement or expulsion occurs. By suturing and securing the device to the uterine wall, the risk of expulsion can be significantly reduced. This approach ensures sustained contraceptive and therapeutic effects, particularly for patients with larger uterine volumes or a history of IUD displacement.

Our team delineated the material selection criteria, operating system, and instrument configuration plan for LNG-IUS nail-type anchoring suture surgery via a clinical case, and illustrated the surgical operation steps in detail.

Through comparative analysis of patients' preoperative and postoperative conditions, integrated with intraoperative imaging and postoperative ultrasonographic data, this study confirms that the innovative nail-type suture technique for LNG-IUS has demonstrated the intended efficacy. It exhibits significant clinical utility, offering an efficacious therapeutic option for patients presenting with abnormally enlarged uterine cavities or recurrent LNG-IUS displacement or expulsion.

Our team pioneered the innovative development of the nail-type anchoring suture technique. This approach departs from conventional suturing methodologies and existing modified fixation techniques. It achieves robust anchoring while obviating the necessity for hysteroscopic visualization during ring removal. This significantly improves clinical outcomes and yields substantial economic advantages.

## Linked entities

- **Chemicals:** levonorgestrel (PubChem CID 13109)

## Full-text entities

- **Chemicals:** LNG (MESH:D016912)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

12 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12832912/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12832912/full.md

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Source: https://tomesphere.com/paper/PMC12832912