# Specific effects of distinct types of adverse childhood experiences on the co-occurrence of non-suicidal self-injury and suicidal behaviors among Chinese adolescents: a latent class analysis

**Authors:** Zhouyan Wang, Wei Chen, Siwei Yang, Gen Chen, Xiaoke Wan, Xia Li, Chang Peng, Hong Wang

PMC · DOI: 10.3389/fpsyt.2025.1698537 · Frontiers in Psychiatry · 2026-01-12

## TL;DR

This study explores how different types of childhood trauma affect the link between self-harm and suicidal behaviors in Chinese teenagers, finding that specific traumas like abuse and neglect increase risks differently.

## Contribution

The study identifies distinct adverse childhood experiences linked to specific patterns of self-harm and suicidal behaviors in adolescents, highlighting gender differences.

## Key findings

- Physical abuse is associated with suicidal ideation among adolescents.
- Emotional abuse and neglect are linked to suicide attempts.
- Neglect has a stronger effect on suicide attempts in one gender compared to the other.

## Abstract

Adverse childhood experiences (ACEs) are well-established risk factors for both non-suicidal self-injury (NSSI) and suicidal behaviors (SBs). Actually, NSSI and SBs often co-occur among adolescents. This study aims to examine the specific effects of ACE types on the co-occurrence of NSSI and three stages of SBs in Chinese adolescents, as well as potential gender differences.

A cross-sectional study was conducted in Chongqing, China. From April to May 2024. A total of 5,143 junior high school students were recruited through stratified cluster sampling. Information was collected through a self-reported questionnaire. Latent class analysis (LCA) was used to identify the co-occurrence patterns of NSSI and SBs. Multinomial logistic regression was employed to examine the independent associations between ACE types and these co-occurrence patterns. Gender differences were assessed using relative odds ratios (ROR).

The prevalence of different ACE types ranged from 2.5% to 23.0%, with 46.4% of participants reporting one or more ACEs. Three co-occurrence patterns of NSSI and SBs were identified: low risk class, suicidal ideation class, and suicide attempts class. Physical abuse (odds ratios [OR] = 1.50, 95% confidence intervals [CI] 1.05 to 2.15) was associated with suicidal ideation class, while emotional abuse (OR = 1.88, 95% CI 1.18 to 3.02) and neglect (OR = 1.45, 95% CI 1.01 to 2.09) were associated with suicide attempts class. A gender difference was found in the association between neglect and suicide attempts class (ROR = 2.34, 95% CI 1.14 to 4.83).

Suicide attempts (SA) and suicidal ideation (SI) tend to co-occur with NSSI among adolescents. Distinct ACE types have unique effects on this co-occurrence, with gender differences. These findings emphasize the importance of considering NSSI and SBs together, and it is more promising to develop tailored anti-ACEs interventions.

## Full-text entities

- **Genes:** AP2B1 (adaptor related protein complex 2 subunit beta 1) [NCBI Gene 163] {aka ADTB2, AP105B, AP2-BETA, CLAPB1}
- **Diseases:** SI (MESH:D001072), NSSI (MESH:D012652), SBs (MESH:D001523), neglect (MESH:D058069)

## Full text

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## References

74 references — full list in the complete paper: https://tomesphere.com/paper/PMC12832740/full.md

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Source: https://tomesphere.com/paper/PMC12832740