# Evidence-based management of stage 2 pressure injuries in country-specific context

**Authors:** Liqun Luo, Liang Hao, Xiulin Wen, Le Tang, Xueyan Liu

PMC · DOI: 10.3389/fmed.2025.1650052 · Frontiers in Medicine · 2026-01-12

## TL;DR

This study shows that evidence-based training improves nurses' ability to manage stage 2 pressure injuries, leading to better patient outcomes in China.

## Contribution

A standardized, evidence-based protocol for stage 2 pressure injury management is developed and tested in a Chinese hospital setting.

## Key findings

- Nurses' knowledge scores significantly improved after evidence-based training.
- Implementation rates of key care indicators increased to 100% in some areas.
- Patient outcomes improved with reduced pain and higher healing rates.

## Abstract

The prevalence of pressure injuries (PI) among hospitalized adults worldwide remains high, posing a serious challenge to global healthcare systems. In China, the scarcity of specialized wound care nurses often leads to the suboptimal management of stage 2 PI by general nursing staff. Therefore, enhancing the wound management capabilities of these non-specialist nurses is crucial for improving healing rates and patient outcomes. This study aimed to systematically summarize the best evidence for stage 2 PI wound management and develop a standardized, evidence-based practice protocol for clinical nurses.

We employed an evidence-based continuous quality improvement model, which comprised four phases: evidence gathering, baseline review, evidence introduction, and effectiveness evaluation. The study was conducted in a tertiary hospital in China, involving 80 skin liaison nurses and 70 patients with stage 2 PI.

Following the implementation of the evidence-based strategy, nurses’ PI knowledge scores (PZ-PUKT) significantly increased from 53.31 ± 4.75 to 56.29 ± 4.72 (p < 0.01). The implementation rate of key review indicators improved markedly, with some increasing from 0 to 100%. Patient outcomes also improved significantly, as evidenced by reduced PUSH scores (p < 0.05), lower pain scores (VAS), and higher wound healing rates in the intervention group.

Research findings indicate that structured, evidence-based nursing strategies significantly enhance nurses’ understanding and implementation of best practices, thereby accelerating wound healing and alleviating patient pain. This study provides a feasible model for implementing standardized stage 2 PI care in resource-limited healthcare settings and lays the groundwork for future multicenter research on intelligent nursing interventions.

## Full-text entities

- **Diseases:** PI (MESH:D003668), pain (MESH:D010146)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

58 references — full list in the complete paper: https://tomesphere.com/paper/PMC12832647/full.md

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Source: https://tomesphere.com/paper/PMC12832647