# Vitamin B12 injection plus traditional Chinese medicine techniques for meralgia paresthetica: a randomized controlled trial

**Authors:** Hongxia Guan, Yong Shi, Xia Zhao

PMC · DOI: 10.3389/fmed.2025.1670225 · Frontiers in Medicine · 2026-01-12

## TL;DR

This study found that combining vitamin B12 injections with traditional Chinese medicine techniques improves treatment outcomes for meralgia paresthetica.

## Contribution

The study demonstrates the added clinical benefit of vitamin B12 injections when combined with TCM techniques for treating lateral femoral cutaneous neuritis.

## Key findings

- The study group had lower pain and numbness scores compared to the control group.
- The study group showed a higher total effective rate and lower recurrence rate.
- The study group had fewer adverse reactions than the control group.

## Abstract

Traditional Chinese medicine (TCM) comprehensive therapy has become the mainstream treatment method for lateral femoral cutaneous neuritis. Vitamin B12 plays an important role in neuropathic diseases. This study aimed to explore the clinical effect of vitamin B12 injection combined with TCM technology in the treatment of lateral femoral cutaneous neuritis.

From January 2022 to January 2024, 126 patients with lateral femoral cutaneous neuritis were selected from our hospital and then randomly divided into a study group and control group. The control group received the methods of pulling, paravertebral positive spot cutaneous needle tapping, and cupping. The study group received vitamin B12 injections on the basis of the methods of pulling, paravertebral positive spot cutaneous needle tapping, and cupping.

After therapy, the pain score and the numbness score in the study group were lower relative to the control group. The total effective rate in the study group was better relative to the control group. The recurrence rate and the incidence of adverse reactions in the study group were lower relative to the control group.

Vitamin B12 injection combined with pulling, paravertebral positive spot cutaneous needle tapping, and cupping has an effective clinical effect in the treatment of lateral femoral cutaneous neuritis.

## Linked entities

- **Chemicals:** Vitamin B12 (PubChem CID 73415824)
- **Diseases:** meralgia paresthetica (MONDO:0023757)

## Full-text entities

- **Diseases:** lateral femoral cutaneous neuritis (MESH:D020428), numbness (MESH:D006987), neuropathic diseases (MESH:D004194), pain (MESH:D010146)
- **Chemicals:** Vitamin B12 (MESH:D014805)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12832628/full.md

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Source: https://tomesphere.com/paper/PMC12832628