# Multimodal imaging findings of primary renal well-differentiated neuroendocrine tumors (carcinoid): a case report and literature review

**Authors:** Bangcheng Wei, Yuge Chen, Yueqin Chen, Shujun Zhang

PMC · DOI: 10.3389/fonc.2025.1597024 · Frontiers in Oncology · 2026-01-12

## TL;DR

This paper presents a rare case of a kidney tumor and reviews how such tumors are diagnosed and managed.

## Contribution

The paper contributes a new case report and literature review on the multimodal imaging and management of rare renal neuroendocrine tumors.

## Key findings

- Primary renal well-differentiated neuroendocrine tumors are rare and have non-specific clinical and imaging features.
- Diagnosis relies on pathological and immunohistochemical analysis, with surgery as the preferred treatment.
- These tumors have low malignant potential and require long-term follow-up for monitoring.

## Abstract

Primary renal well-differentiated neuroendocrine tumors (NETs) are rare. Due to their non-specific nature, the detection and monitoring of NETs remain highly challenging. Here, we report a case of a 45-year-old man who was admitted after an incidental finding of a space-occupying lesion in the kidney during a routine physical examination. The patient underwent CT and MRI multimodal imaging, followed by pathological and immunohistochemical analysis after surgery, leading to a diagnosis of well-differentiated renal NET. He was subsequently followed up for a long period. A review of the literature, in conjunction with this case, revealed that these tumors present with non-specific clinical and imaging features. Diagnosis primarily relies on pathological and immunohistochemical evaluation. Well-differentiated renal neuroendocrine tumors are associated with low malignant potential and a favorable prognosis. Surgical resection is the treatment of choice, and long-term follow-up is essential to monitor the patient’s condition. By combining this case with existing literature, we aim to provide valuable insights for clinicians in the diagnosis and management of renal NETs.

## Full-text entities

- **Diseases:** renal NET (MESH:D006030), carcinoid (MESH:D002276), tumors (MESH:D009369), NETs (MESH:D018358)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12832449/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12832449/full.md

## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC12832449/full.md

---
Source: https://tomesphere.com/paper/PMC12832449