# Effectiveness of self-guided virtual reality exposure therapy for social anxiety disorder: a systematic review and meta-analysis protocol

**Authors:** Yiyuan Li, Jifeng Shen, Guanghui Huang

PMC · DOI: 10.3389/fpubh.2025.1735471 · Frontiers in Public Health · 2026-01-12

## TL;DR

This paper outlines a systematic review protocol to evaluate the effectiveness of self-guided virtual reality exposure therapy for treating social anxiety disorder.

## Contribution

The study introduces a systematic review protocol to assess SGVRET's efficacy for SAD, addressing a gap in current literature.

## Key findings

- The review will use PRISMA guidelines and include randomized controlled trials.
- Findings will guide the design and optimization of digital interventions for social anxiety.

## Abstract

Social Anxiety Disorder (SAD) is a prevalent anxiety disorder within contemporary mental health practice, attracting increasing attention. Self-guided virtual reality exposure therapy (SGVRET) has been demonstrated to be an effective intervention for SAD in multiple studies. Although research suggests SGVRET may alleviate SAD symptoms, systematic reviews examining its efficacy in treating SAD remain lacking.

This protocol outlines a systematic review designed to assess the efficacy of SGVRET as a intervention for SAD. The study adheres to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Included studies must be randomised controlled trials employing SGVRET as the intervention. A comprehensive search will be conducted across databases including PubMed, Embase, the Cochrane Library, Web of Science, and Scopus, covering studies from the inception of each database up to September 2025. Data synthesis will be performed via meta-analysis or narrative synthesis based on study homogeneity. Furthermore, Stata version 18.0 software will be employed for meta-analysis.

This review will systematically evaluate the efficacy of SGVRET in social anxiety disorder, providing an evidence base for its standardised application and assessment among individuals with SAD. Findings from relevant studies will also offer actionable guidance for the design, implementation, and optimisation of digital interventions targeting those with social anxiety.

https://www.crd.york.ac.uk/PROSPERO/view/CRD420251151820, identifier CRD420251151820.

## Linked entities

- **Diseases:** Social Anxiety Disorder (MONDO:0001247)

## Full-text entities

- **Diseases:** anxiety disorder (MESH:D001008), SAD (MESH:D000072861)

## Full text

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## Figures

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## References

60 references — full list in the complete paper: https://tomesphere.com/paper/PMC12832236/full.md

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Source: https://tomesphere.com/paper/PMC12832236