# Thrombotic Storm: A Challenging Case of Catastrophic Antiphospholipid Syndrome

## TL;DR

A 68-year-old woman with multiple health conditions developed a severe and rare form of antiphospholipid syndrome, leading to multiorgan ischemia.

## Contribution

This case highlights the rare and severe presentation of catastrophic antiphospholipid syndrome in a patient with pre-existing autoimmune conditions.

## Key findings

- The patient showed initial improvement with ciprofloxacin but later developed severe symptoms.
- Abdominopelvic CT scan revealed multiorgan ischemia, suggesting catastrophic antiphospholipid syndrome.
- The case underscores the challenges in diagnosing and managing CAPS in patients with complex medical histories.

## Abstract

We present the clinical case of a 68-year-old woman with a history of cerebrovascular disease, primary Sjögren’s syndrome, and suspected antiphospholipid syndrome, admitted for acute diarrhea and fever. She showed good clinical and laboratory improvement under ciprofloxacin until the fifth day of hospitalization, when she developed abdominal pain with guarding, fever, and vomiting. Laboratory tests revealed elevated inflammatory markers and rhabdomyolysis. An abdominopelvic CT scan showed multiorgan ischemia, raising the suspicion of catastrophic antiphospholipid syndrome (CAPS).