# Asymptomatic central venous occlusion secondary to central venous catheter-use complicating pacemaker implantation: a leadless solution

**Authors:** James Baudry, Christopher Cassidy, Kanarath Balachandran

PMC · DOI: 10.1093/omcr/omaf292 · Oxford Medical Case Reports · 2026-01-25

## TL;DR

A patient with blocked central veins due to past chemotherapy had a pacemaker implanted without wires, showing a new solution for difficult cases.

## Contribution

The paper presents a leadless pacemaker as a novel solution for patients with central venous occlusion.

## Key findings

- Leadless pacemaker implantation via the femoral vein was successful in a patient with central venous occlusion.
- Central venous occlusion can be caused by prior central venous catheter use during chemotherapy.
- Pre-procedural imaging helps identify central venous occlusion and guide device strategy.

## Abstract

Abnormal central venous anatomy can obstruct cardiac-device implantation. We report a 54-year-old patient found to be in complete heart-block after identification of profound bradycardia, requiring cardiac-pacing. Echocardiography revealed systolic dysfunction, prompting a plan for cardiac resynchronization therapy. Conventional lead placement was impossible due to failed guide-wire advancement bilaterally. Peri-procedural venography demonstrated attenuation of both brachiocephalic veins and contrast-enhanced computed tomography confirmed complete central venous occlusion (CVO). Further history identified previous chemotherapy delivered via central venous catheters, as the likely aetiology for the CVO and systolic dysfunction. Alternative pacing options were considered. Ultimately the leadless Micra-AV-pacemaker was successfully implanted via the femoral vein with good clinical recovery. This unique case highlights CVO as an obstacle to cardiac-device implantation, with specific patients at increased risk. Pre-procedural imaging in those at-risk may reduce procedure failure and facilitate appropriate device strategy choice. Leadless pacing provides a safe, effective alternative in cases of CVO.

## Full-text entities

- **Diseases:** systolic dysfunction (MESH:D006331), bradycardia (MESH:D001919), heart-block (MESH:D006327), CVO (MESH:D015356)
- **Chemicals:** Micra (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12832022/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12832022/full.md

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Source: https://tomesphere.com/paper/PMC12832022