# A Combination Of Vein Of Galen Aneurysmal Malformation And Bovine Aortic Arch In Newborn: A Case Report

**Authors:** Krishna Deo Mandal, Kalpana Subedi, Unnati Amatya, Janak Pathak

PMC · DOI: 10.31729/jnma.8987 · JNMA: Journal of the Nepal Medical Association · 2025-05-31

## TL;DR

A rare case of a newborn with a brain blood vessel malformation and an unusual aortic arch is reported, highlighting the challenges in treatment.

## Contribution

This case report documents the rare coexistence of Vein of Galen aneurysmal malformation and bovine aortic arch in a newborn.

## Key findings

- Vein of Galen aneurysmal malformation can present with severe heart failure and poor outcomes.
- Coexistence with aortic arch anomalies increases treatment risks and mortality.
- The Bicetre score helps determine treatment options and prognosis.

## Abstract

Vein of Galen aneurysmal malformation is a rare intracranial arteriovenous malformation, coexistence with aortic arch anomalies is even more uncommon, carry high risk of morbidity and mortality related to endovascular procedure and poor neurological outcome. Vein of Galen aneurysmal malformation is a dilated venous pouch, a persistence of the embryonic median prosencephalic vein of Markowski. Often presents with high output cardiac failure, severe pulmonary hypertension, and systemic steal leading to hemodynamic compromise and multi organ failure. Bicetre score scale determines the potential treatment option and prognosis of the disease. Aim of the medical treatment is initial stabilization of life threatening condition of severe heart failure followed by the definitive treatment with endovascular embolization. Treatment is a big challenge, specially if coexistence with aortic arch anomalies which increases the morbidity and mortality. We describe a term neonate found to have vein of Galen aneurysmal malformation associated with bovine aortic arch.

## Linked entities

- **Diseases:** pulmonary hypertension (MONDO:0005149)

## Full-text entities

- **Diseases:** PDA (MESH:D004374), Galen Aneurysmal Malformation (MESH:C536535), coagulation (MESH:D001778), cardiac murmur (MESH:D006337), BAA (MESH:D002418), AV malformation (MESH:D054537), vascular injury (MESH:D057772), hepatomegaly (MESH:D006529), brain damage (MESH:D001925), intellectual disability (MESH:D008607), foramen ovale (MESH:D054092), hydrocephalus (MESH:D006849), PAH (MESH:D006976), arteriovenous fistula (MESH:D001164), infarction (MESH:D007238), cardiac failure (MESH:D006333), TR (MESH:D014262), cardiac anomalies (MESH:D006331), cardiomegaly (MESH:D006332), steal (MESH:D013349), cyanosed (MESH:D003490), renal failure (MESH:D051437), edema (MESH:D004487), fetal anomaly (MESH:D000013), anomalous aortic arch (MESH:D001015), headache (MESH:D006261), inflammatory (MESH:D007249), respiratory distress (MESH:D012128), neurological deficits (MESH:D009461), Congenital cardiac anomaly (MESH:C535853), seizure (MESH:D012640), multi organ failure (MESH:D009102), hemorrhage (MESH:D006470), aortic arch anomalies (MESH:C535542), intracranial hemorrhage (MESH:D020300), cerebral arteriovenous malformation (MESH:D002538)
- **Chemicals:** vitamin K (MESH:D014812), Frusemide (MESH:D005665), sildenafil (MESH:D000068677), milrinone (MESH:D020105), oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606], Bos taurus (bovine, species) [taxon 9913]

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12831820/full.md

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Source: https://tomesphere.com/paper/PMC12831820