# Insulinoma in a Young Patient With Focal Seizures: A Case Report of a Neurological Diagnostic Challenge

**Authors:** María Valerio López, Christopher Kaleb Romero Ríos, Mohammed Zahran, Allan Mariano Bodan Campbell, Amilcar Alfaro, Jorge Chamorro Flores

PMC · DOI: 10.1002/ccr3.71931 · Clinical Case Reports · 2026-01-24

## TL;DR

A young patient with focal seizures was found to have an insulinoma, highlighting the importance of checking for low blood sugar in similar cases.

## Contribution

This case report emphasizes the need to consider insulinoma in patients with fasting-associated focal seizures to avoid diagnostic delays.

## Key findings

- Insulinomas can present with symptoms similar to refractory epilepsy, causing misdiagnosis.
- Hypoglycemia should be evaluated in patients with fasting-associated focal seizures.
- Early diagnosis and surgical resection can cure insulinomas and reverse neurological symptoms.

## Abstract

Insulinomas can mimic refractory epilepsy, leading to diagnostic delays. Hypoglycemia should be ruled out in patients with fasting‐associated focal seizures. Timely diagnosis via Whipple's triad and surgical resection offers a complete cure and reversal of neuropsychiatric symptoms.

## Linked entities

- **Diseases:** insulinoma (MONDO:0024677)

## Full-text entities

- **Diseases:** refractory epilepsy (MESH:D000069279), neuropsychiatric symptoms (MESH:D001523), Insulinoma (MESH:D007340), Hypoglycemia (MESH:D007003), Seizures (MESH:D012640)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12831638/full.md

## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12831638/full.md

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Source: https://tomesphere.com/paper/PMC12831638