# An Unusual Presentation of an Epidermoid Cyst Near the Nasolabial Fold: A Case Report

**Authors:** Abira Chattopadhyay, Md Arif Hossain, Aritra Chatterjee, Nayana De, Basabdatta Ghosh

PMC · DOI: 10.7759/cureus.100019 · Cureus · 2025-12-24

## TL;DR

A 31-year-old man had a rare epidermoid cyst near his nose-lip fold, which was successfully removed with no recurrence after a year.

## Contribution

This case report presents an unusual location for an epidermoid cyst and demonstrates the effectiveness of an intraoral surgical approach.

## Key findings

- The lesion was confirmed as an epidermoid cyst through histopathology.
- The intraoral approach provided good aesthetic and functional outcomes with no recurrence.
- The case emphasizes the need to consider epidermoid cysts in cheek mass diagnoses.

## Abstract

Epidermoid cysts are benign, slow-growing lesions arising from epidermal cell proliferation within the dermis. Although common on the scalp and trunk, they rarely occur in the head and neck region, particularly the cheek. We report a 31-year-old male with a painless, progressive swelling lateral to the right nasolabial fold for two years. Ultrasonography and fine-needle aspiration yielded keratinous material suggestive of an epidermoid cyst. The lesion was excised entirely via an intraoral approach under general anesthesia. Histopathology showed a cyst lined by orthokeratinized stratified squamous epithelium without adnexal structures, confirming an epidermoid cyst. Healing was uneventful, and no recurrence was noted after one year. This case highlights the importance of considering epidermoid cysts in the differential diagnosis of cheek masses and demonstrates that an intraoral approach provides excellent aesthetic and functional results.

## Linked entities

- **Diseases:** epidermoid cyst (MONDO:0007547)

## Full-text entities

- **Diseases:** cheek masses (MESH:C536030), Epidermoid Cyst (MESH:D004814), swelling (MESH:D004487)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12831495/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12831495/full.md

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Source: https://tomesphere.com/paper/PMC12831495