# Disseminated Invasive Aspergillosis in a Young Patient With Chronic Alcohol Use and Seemingly Preserved Immunocompetence: A Case Report

**Authors:** Kumail Khandwala, Hiba Sawliha Syed, Shayan Sirat Maheen Anwar, Sehar Suleman, Khabab Abbasher Hussien Mohamed Ahmed

PMC · DOI: 10.1002/ccr3.71943 · Clinical Case Reports · 2026-01-24

## TL;DR

A young patient with chronic alcohol use developed invasive aspergillosis, showing that fungal infections can occur even in seemingly healthy individuals.

## Contribution

This case report adds to the understanding of invasive aspergillosis in immunocompetent individuals.

## Key findings

- Invasive aspergillosis occurred in a patient with chronic alcohol use but no overt immunodeficiency.
- The case underscores the need to consider fungal infections in patients with chronic respiratory symptoms and risk factors.

## Abstract

Invasive aspergillosis, though typically seen in immunocompromised patients, can also affect immunocompetent individuals and mimic pulmonary malignancy. This case highlights the importance of considering fungal infections in the differential diagnosis of chronic respiratory symptoms, particularly in patients with risk factors such as heavy alcohol consumption, that may impair immune function.

## Linked entities

- **Diseases:** invasive aspergillosis (MONDO:0000240)

## Full-text entities

- **Diseases:** pulmonary malignancy (MESH:D009369), fungal infections (MESH:D009181), Aspergillosis (MESH:D001228)
- **Chemicals:** alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12831207/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12831207/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC12831207/full.md

---
Source: https://tomesphere.com/paper/PMC12831207