# Integrating AI into Dentistry: Technical Pathways and Clinical Applications in Oral Diseases–A Comprehensive Overview **Authors:** Ying Yuan, Hao Zhou, Bo Wang, Chengrun Li, Baijuan Gong, Zhimin Li PMC · DOI: 10.1016/j.identj.2025.109336 · International Dental Journal · 2026-01-14 ## TL;DR This paper reviews how AI is being used in dentistry to improve diagnosis and treatment of oral diseases. ## Contribution The paper provides a comprehensive overview of AI applications in dentistry, including technical pathways and clinical scenarios. ## Key findings - AI improves diagnostic accuracy in oral diseases. - AI supports clinical decision-making through various neural network architectures. - The paper identifies limitations and future directions for AI in dentistry. ## Abstract The application of artificial intelligence (AI) technologies in the management of oral diseases is rapidly increasing, encompassing etiopathogenesis, disease course, diagnosis, treatment plans, and postoperative care. AI demonstrates exceptional performance in enhancing diagnostic accuracy and supporting clinical decision-making. This review provides a comprehensive overview of AI in dentistry, elucidating the neural network architectures and major implementation methods of AI. It focuses on specific application scenarios of AI-based models and evaluates their performance, and additionally highlights the limitations and promising future directions, providing insights to advance the clinical applications of AI in dentistry. ## Full-text entities - **Genes:** NINL (ninein like) [NCBI Gene 22981] {aka NLP} - **Diseases:** alveolar bone loss (MESH:D016301), ameloblastic carcinoma (MESH:D009810), dentigerous cysts (MESH:D003803), erythema multiforme (MESH:D004892), supernumerary teeth (MESH:D014096), Cysts (MESH:D003560), Tumor (MESH:D009369), AI (MESH:C538142), Ameloblastoma (MESH:D000564), OLP (MESH:D017676), discoid lupus erythematosus (MESH:D008179), lymphoma (MESH:D008223), periapical lesion (MESH:D010483), Head and neck cyst (MESH:D006258), lymph node metastasis (MESH:D008207), disc dislocations (MESH:D055959), Periodontitis (MESH:D010518), osteoarthritis (MESH:D010003), mandibular protrusion (MESH:D008338), ECC (MESH:D003731), odontogenic cysts (MESH:D009807), pulpitis (MESH:D011671), OSCC (MESH:D000077195), impacted (MESH:D004834), DL (MESH:D007859), TMJOA (MESH:D013706), TMJ disc displacement (MESH:D007405), salivary gland diseases (MESH:D012466), jawbone lesion (MESH:D009059), odontogenic lesions (MESH:D009808), peri-implant diseases (MESH:D057873), TMD (MESH:D013705), crowding (MESH:D008310), Jawbone fractures (MESH:D050723), benign lymphadenopathy (MESH:D008206), OLK (MESH:D007972), Class III malocclusion (MESH:D008313), periapical cysts (MESH:D011842), maxillary sinusitis (MESH:D015523), oral cancer (MESH:D009062), mandibular fracture (MESH:D008337), condylar fractures (MESH:D000092483), Class II malocclusion (MESH:D008312), Postoperative complications (MESH:D011183), root caries (MESH:D017213), dental disease (MESH:D009057), bone loss (MESH:D001847), metastatic lymph nodes (MESH:D000072717), Jawbone trauma (MESH:D014947), cleft lip (MESH:D002971), periodontal disease (MESH:D010510), tongue SCC (MESH:D014060), OPMDs (MESH:C537245) - **Chemicals:** hematoxylin and eosin (-), H&E (MESH:D006371) - **Species:** Homo sapiens (human, species) [taxon 9606] ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12830296/full.md ## Figures 4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12830296/full.md ## References 152 references — full list in the complete paper: https://tomesphere.com/paper/PMC12830296/full.md --- Source: https://tomesphere.com/paper/PMC12830296