# A reirradiation workflow for managing patients with treatments planned in a multi-TPS environment

**Authors:** Jason Vickress, Anders Celinski, Barbara Millman, David A. Palma, Donna H. Murrell

PMC · DOI: 10.1016/j.tipsro.2026.100377 · Technical Innovations & Patient Support in Radiation Oncology · 2026-01-07

## TL;DR

This paper describes a workflow for safely managing reirradiation treatments using a system that works across different treatment planning software.

## Contribution

The novel contribution is a TPS-vendor agnostic workflow for dose accumulation and evaluation in reirradiation.

## Key findings

- A TPS-agnostic workflow improves safety and efficiency in reirradiation programs.
- Accurate dose accumulation is critical for managing complex reirradiation cases.
- Multidisciplinary communication is essential for successful reirradiation treatment planning.

## Abstract

•Reirradiation is increasing. Dedicated workflows, like those described here, are required to manage these complex cases.•A TPS-vendor agnostic workflow for dose accumulation and evaluation is described.

Reirradiation is increasing. Dedicated workflows, like those described here, are required to manage these complex cases.

A TPS-vendor agnostic workflow for dose accumulation and evaluation is described.

Reirradiation is becoming more common. Safe and effective implementation relies on accurate dose accumulation methodology, complex treatment planning, and multidisciplinary communication. Clinical workflow guidance to address these challenges is needed. Herein we report a TPS-agnostic reirradiation workflow, developed at our institution, that facilitates comprehensive cumulative dose evaluation and can improve safety and efficiency in reirradiation programs.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12830171/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12830171/full.md

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Source: https://tomesphere.com/paper/PMC12830171