# Chronic Ketamine Toxicity Involving both Urinary and Hepatobiliary Systems

**Authors:** Alexander Cotza, Liesbeth Meylaerts

PMC · DOI: 10.5334/jbsr.4197 · Journal of the Belgian Society of Radiology · 2026-01-20

## TL;DR

This paper reports a case of chronic ketamine abuse causing both urinary and liver bile system damage in a young adult.

## Contribution

Highlights ketamine toxicity as a multisystem disorder affecting both urinary and hepatobiliary systems.

## Key findings

- Chronic ketamine abuse can cause uropathy and cholangiopathy simultaneously.
- Hepatobiliary manifestations of ketamine toxicity are under-recognized in clinical practice.

## Abstract

Chronic ketamine abuse is a well-recognized cause of lower urinary tract injury. Hepatobiliary manifestations are less frequently reported. A case is presented of concomitant ketamine-induced uropathy and cholangiopathy in a young adult. This underscores the importance of considering ketamine toxicity as a multisystem disorder.

Teaching point: Beyond the well-recognized urinary tract involvement, radiologists attention is drawn to hepatobiliary manifestations of chronic ketamine toxicity.

## Linked entities

- **Chemicals:** ketamine (PubChem CID 3821)

## Full-text entities

- **Diseases:** urinary tract injury (MESH:D014570), Toxicity (MESH:D064420), uropathy (MESH:C536483)
- **Chemicals:** Ketamine (MESH:D007649)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12829456/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12829456/full.md

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Source: https://tomesphere.com/paper/PMC12829456