# Nicotine Analogues in Oral Pouch Products and Associated Marketing Claims

**Authors:** Joseph R. Ciancio, Lakshmi Kumar, Kriti Rastogi, Meghan B. Moran, Lauren Czaplicki, Michelle K. Page, Hasan Jamil, Maciej L. Goniewicz, Tory R. Spindle

PMC · DOI: 10.1001/jamanetworkopen.2025.54883 · 2026-01-22

## TL;DR

This study examines nicotine-containing oral pouch products in the US and the marketing claims associated with them.

## Contribution

The study provides an analysis of nicotine analogues in oral pouch products and their marketing claims in the US.

## Key findings

- Nicotine analogues were identified in various oral pouch products.
- Marketing claims associated with these products were documented.

## Abstract

This case series study analyzed the contents of nicotine analoge pouch products available in the US and documented associated marketing claims.

## Linked entities

- **Chemicals:** nicotine (PubChem CID 942)

## Full-text entities

- **Diseases:** addiction (MESH:D019966)
- **Chemicals:** Nicotinamide (MESH:D009536), Nicotine (MESH:D009538), (S)-6-methylnicotine (-)
- **Species:** Nicotiana tabacum (American tobacco, species) [taxon 4097], Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12828627