# Chemistry in Transformation: A European Moment

**Authors:** Javier García‐Martínez

PMC · DOI: 10.1002/anie.202526116 · 2025-12-19

## TL;DR

Europe's chemical industry is at a crossroads, needing to balance decarbonization, circularity, and digitalization to remain competitive and sustainable.

## Contribution

The paper outlines the transformative challenges and opportunities for Europe's chemical industry, emphasizing the need for responsible innovation and policy coordination.

## Key findings

- Europe's chemical industry faces structural disadvantages like high energy costs and fragmented regulation.
- Breakthroughs in electrification, catalysts, and AI-driven synthesis could enhance competitiveness and sustainability.
- Resilience and circular design are critical for the industry to withstand shocks and scale technologies.

## Abstract

Chemistry stands at a pivotal juncture, facing unprecedented expectations to decarbonize, enable circularity, and sustain essential sectors, while remaining globally competitive. Europe embodies these pressures acutely. Although the region excels in frontier research, structural disadvantages such as high energy and feedstock costs, fragmented regulation, slow permitting, and constrained capital limit its capacity to translate scientific leadership into industrial success. The energy crisis of 2022 exposed long‐standing vulnerabilities, triggering capacity closures in foundational value chains such as ammonia and olefins and accelerating the erosion of Europe`s market share. Yet chemistry`s transformation is driven not only by economic asymmetry, but by deeper shifts: the urgency of decarbonization, the need for molecular circularity, and the integration of digital technologies into discovery and manufacturing. Breakthroughs in electrification, advanced catalysts, CO2 conversion, self‐driving laboratories, and AI‐enabled synthesis offer pathways to both competitiveness and sustainability, but their impact depends on coordinated infrastructure, stable policy, and risk‐tolerant finance. Crucially, this moment also demands responsibility and resilience: chemistry must be circular by design, transparent in its data, and robust enough to withstand shocks, diversify feedstocks, and scale technologies reliably. Europe`s leadership will hinge on embedding these principles into how chemistry is imagined, taught, and deployed.

Europe’s chemical industry faces a defining moment. Decarbonization, circularity, and digitalization are reshaping competitiveness amid high energy costs and investment challenges. Integrating responsible and resilient chemistry with innovation, infrastructure, and policy is essential to translate scientific leadership into sustainable industrial renewal and long‐term industrial leadership.

## Full-text entities

- **Chemicals:** olefins (MESH:D000475), ammonia (MESH:D000641), CO2 (MESH:D002245)

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12828443/full.md

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Source: https://tomesphere.com/paper/PMC12828443