# Acute Renal Infarction as an Initial Manifestation of Factor V Leiden Mutation: A Case Report

## TL;DR

A woman with no prior health issues developed a kidney infarction due to a blood clotting disorder called Factor V Leiden, highlighting the need to consider such inherited conditions in similar cases.

## Contribution

This case report presents a rare manifestation of Factor V Leiden mutation as an initial symptom of acute renal infarction.

## Key findings

- A previously healthy woman experienced acute renal infarction due to Factor V Leiden mutation.
- Factor V Leiden can present as renal infarction even in the absence of typical risk factors.
- Thrombophilia should be considered in the differential diagnosis of acute renal infarction.

## Abstract

Factor V Leiden is one of the most prevalent forms of inherited thrombophilia. While its usual presentation is a deep vein thrombosis and pulmonary embolism, it can manifest less commonly as a renal infarction. Here, we describe a case of a previously healthy woman who was found to have a renal infarction triggered by a hypercoagulable state associated with the Factor V Leiden mutation. This case highlights the importance of considering thrombophilia as a differential diagnosis in cases of insidious acute renal infarction, especially in patients with no identified risk factors.