# Pulmonary Tuberculosis: The Great Mimicker of Lung Cancer

**Authors:** Laura Corrales‐Diaz Pomatto‐Watson, Hershan Singh Johl, Karleen Meiklejohn

PMC · DOI: 10.1002/ccr3.71919 · 2026-01-22

## TL;DR

This paper discusses a case where tuberculosis was mistaken for lung cancer due to similar symptoms and imaging results.

## Contribution

The paper presents a clinical case highlighting the diagnostic challenge of distinguishing pulmonary tuberculoma from lung cancer.

## Key findings

- A solitary pulmonary nodule was found in a patient with a history of TB exposure.
- Biopsy confirmed the nodule was due to tuberculosis, not cancer.

## Abstract

Though tuberculosis (TB) is an ancient pathogen, diagnosis remains challenging. Distinguishing pulmonary tuberculoma, a rare manifestation of TB, from lung cancer is critical. We report an 85‐year‐old woman with a smoking history and TB‐endemic exposure, presenting with fatigue and anorexia. Imaging revealed a solitary pulmonary nodule (SPN), with biopsy confirming TB.

Computed tomography (CT) scan of the chest with contrast indicating a soft tissue density in the left upper lobe.

## Linked entities

- **Diseases:** pulmonary tuberculosis (MONDO:0006052), lung cancer (MONDO:0005138), tuberculosis (MONDO:0018076)

## Full-text entities

- **Diseases:** pulmonary tuberculoma (MESH:D014375), anorexia (MESH:D000855), Pulmonary Tuberculosis (MESH:D014397), nodule (MESH:D016606), Lung Cancer (MESH:D008175), fatigue (MESH:D005221), SPN (MESH:D003074), TB (MESH:D014376)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12828060/full.md

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Source: https://tomesphere.com/paper/PMC12828060