# COVID-19 vaccine acceptance among non-communicable disease patients in Haiti

**Authors:** Evyrna Toussaint, Calixte Dawson, Darius L. Fénelon, Sarah M. Morris, Fediana Enoise, Rosemy Lolagne, Maurice Junior Chery, Kobel Dubique, Mary Clisbee, Davidson Laneau, Gene F. Kwan

PMC · DOI: 10.3389/fpubh.2025.1697746 · 2026-01-09

## TL;DR

This study explores how non-communicable disease patients in rural Haiti feel about the COVID-19 vaccine and what factors influence their acceptance or hesitancy.

## Contribution

The study provides insights into vaccine hesitancy and knowledge gaps among NCD patients in rural Haiti, highlighting the need for culturally tailored interventions.

## Key findings

- 34% of unvaccinated NCD patients in rural Haiti reported vaccine acceptance.
- High awareness of COVID-19 exists, but accurate knowledge of symptoms and prevention is limited.
- Significant hesitancy was observed among those preferring traditional medicine over vaccination.

## Abstract

The COVID-19 pandemic continues to challenge global health, with individuals suffering from cardiometabolic conditions such as hypertension and diabetes at increased risk of severe complications. While vaccination is a key preventive measure, acceptance varies due to factors including safety concerns and cultural beliefs. This study assesses COVID-19 vaccine acceptance and hesitancy, along with knowledge, attitudes, and practices (KAP) related to COVID-19 among non-communicable disease (NCD) patients in rural central Haiti.

We conducted a cross-sectional study from September 2021 to January 2022 at the outpatient NCD clinic of Hopital Universitaire de Mirebalais. A total of 229 NCD patients were surveyed to evaluate vaccine acceptance, hesitancy, and KAP regarding COVID-19. Data were analyzed using Chi-squared tests, T-tests, and logistic regression.

Participants’ average age was 56.2 years, with 75.1% being female. Vaccine acceptance was reported by 34% of unvaccinated individuals, with significant hesitancy among those favoring traditional medicine. Despite high awareness of COVID-19 (99.6%), accurate knowledge of symptoms and preventive measures was limited.

Targeted interventions addressing vaccine hesitancy among people with non-communicable diseases in rural Haiti are crucial. Culturally sensitive education delivered through community health workers could improve vaccine uptake in this high-risk population.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015), COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** hypertension (MESH:D006973), diabetes (MESH:D003920), cardiometabolic conditions (MESH:D024821), COVID-19 (MESH:D000086382), NCD (MESH:D000073296)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12827755/full.md

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Source: https://tomesphere.com/paper/PMC12827755