# Pericardiectomy for Constrictive and Recurrent Pericarditis: State of the Art Update

**Authors:** Kristina Krzelj, Maria Bakaeen, Tom Kai Ming Wang, Allan Klein, Saberio Lo Presti Vega, Christine Jellis, Deborah Kwon, Michael Tong, Shinya Unai, Marijan Koprivanac

PMC · DOI: 10.1007/s11886-025-02339-z · Current Cardiology Reports · 2026-01-22

## TL;DR

This paper reviews the best surgical practices for treating constrictive and recurrent pericarditis, emphasizing radical pericardiectomy for better outcomes.

## Contribution

The paper updates the state-of-the-art surgical approach for pericardiectomy, advocating radical or complete resection over partial.

## Key findings

- Radical pericardiectomy is preferred over partial to reduce recurrence risks.
- Cardiopulmonary bypass can improve the safety and completeness of the procedure.
- Multidisciplinary care in experienced centers is crucial for optimal results.

## Abstract

This review provides a contemporary surgical view on constrictive and recurrent pericarditis.

Cardiac magnetic resonance imaging, echocardiography, and heart catheterization are complementary tools for diagnosis and management of patients considered for pericardiectomy. Radical pericardiectomy, unlike total/complete, represents the most extensive resection. Radical or total/complete pericardiectomy via median sternotomy is preferred over partial for both recurrent and constrictive pericarditis, to minimize the risk of symptoms and/or constriction recurrence. Utilization of cardiopulmonary bypass may facilitate the completeness and safety of the procedure. In surgical planning, attention should be paid to intraoperative challenges, especially low cardiac output syndrome, tricuspid regurgitation, and coronary injury. A multidisciplinary approach in experienced centers is essential to optimize outcomes.

Radical or complete pericardiectomy is advised over partial to avoid the symptoms or constriction recurrence owing to the remaining pericardium. Further research is mandatory to identify the optimal timing and precise extent of pericardiectomy.

## Linked entities

- **Diseases:** constrictive pericarditis (MONDO:0006711)

## Full-text entities

- **Genes:** IL1A (interleukin 1 alpha) [NCBI Gene 3552] {aka IL-1 alpha, IL-1A, IL1, IL1-ALPHA, IL1F1}
- **Diseases:** RV failure (MESH:D051437), cytopenia (MESH:D006402), Pericarditis (MESH:D010493), constrictive pericarditis (MESH:D010494), pulmonary fibrosis (MESH:D011658), tuberculous constrictive pericarditis (MESH:D010495), ischemic (MESH:D002545), coronary injury (MESH:D003323), pericardial effusion (MESH:D010490), autoimmune disease (MESH:D001327), systemic lupus erythematosus (MESH:D008180), adhesions (MESH:D000267), tuberculosis (MESH:D014376), bleeding (MESH:D006470), myocarditis (MESH:D009205), restrictive cardiomyopathy (MESH:D002313), TR (MESH:D014262), rheumatoid arthritis (MESH:D001172), LCOS (MESH:D002303), overdistension of the right ventricle (MESH:C535682), pericardial calcification (MESH:D008476), cardiogenic cirrhosis (MESH:D005355), heart failure (MESH:D006333), trauma (MESH:D014947), death (MESH:D003643), coronary disease (MESH:D003327), pericardial edema (MESH:D004487), myocardial involvement (MESH:C564676), chest pain (MESH:D002637), opportunistic infections (MESH:D009894), cardiac injury (MESH:D006331), Pericardial Inflammation (MESH:D007249), cardiomyopathy (MESH:D009202), coronary artery injury (MESH:D003324), myocardial infarction (MESH:D009203)
- **Chemicals:** antiinflammatory medications (-), colchicine (MESH:D003078)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12827344/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12827344/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12827344/full.md

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Source: https://tomesphere.com/paper/PMC12827344