# Primary urothelial carcinoma of the prostate: report of two cases and review of the literature

## TL;DR

This paper reports two rare cases of primary urothelial carcinoma of the prostate and discusses the challenges in diagnosis and treatment.

## Contribution

The paper adds two new cases to the limited literature on this rare prostate cancer type.

## Key findings

- Primary urothelial carcinoma of the prostate is extremely rare and often misdiagnosed.
- The prognosis for this condition is poor, with no established treatment consensus.
- Two new cases were reported with a median follow-up of 14 months.

## Abstract

Transitional cell carcinoma of the prostatic urethra was first described and reported in 1963. Primary urothelial carcinoma of the prostate is an extremely rare disease, often misdiagnosed with other entities, particularly with urothelial carcinoma of the bladder involving the prostatic tissue. There are only dozens of cases of primary urothelial carcinoma in the prostate reported in the literature. The prognosis after diagnosis is reported to be poor and there is no consensus among experts concerning its proper treatment and follow-up. Herein, we report two cases of patients diagnosed with this entity with a median follow-up of 14 months.